The Value of Using Green Extraction Techniques to Enhance Polyphenol Content and Antioxidant Activity in <i>Nasturtium officinale</i> Leaves

Increasing research is being directed toward the production of value-added products using plant extracts that are super-fortified with antioxidants. In this study, the extraction parameters for bioactive compounds (such as polyphenols) from <i>Nasturtium officinale</i> leaves and their a...

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Main Authors: Eva Naoum, Aikaterini Xynopoulou, Konstantina Kotsou, Theodoros Chatzimitakos, Vassilis Athanasiadis, Eleni Bozinou, Stavros I. Lalas
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Applied Sciences
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Online Access:https://www.mdpi.com/2076-3417/14/22/10739
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author Eva Naoum
Aikaterini Xynopoulou
Konstantina Kotsou
Theodoros Chatzimitakos
Vassilis Athanasiadis
Eleni Bozinou
Stavros I. Lalas
author_facet Eva Naoum
Aikaterini Xynopoulou
Konstantina Kotsou
Theodoros Chatzimitakos
Vassilis Athanasiadis
Eleni Bozinou
Stavros I. Lalas
author_sort Eva Naoum
collection DOAJ
description Increasing research is being directed toward the production of value-added products using plant extracts that are super-fortified with antioxidants. In this study, the extraction parameters for bioactive compounds (such as polyphenols) from <i>Nasturtium officinale</i> leaves and their antioxidant properties were optimized using response surface methodology. The optimization procedure examined the effects of the extraction temperature, time, and solvent composition on conventional magnetic stirring (ST). In addition, the impacts of two green techniques—pulsed electric field (PEF) and ultrasound (US)—were evaluated individually and in combination to assess their potential to enhance the extraction of the compounds. According to our findings, under the proposed extraction conditions (a combination of PEF, US, and ST as a extraction technique, 50% ethanolic solvent, for 30 min at 80 °C). <i>N. officinale</i> leaf extract proved to be an excellent source of bioactive compounds, with extracts containing rosmarinic acid (3.42 mg/g dried weight (dw)), chlorogenic acid (3.13 mg/g dw), total polyphenol content (28.82 mg of gallic acid equivalents (GAE)/g dw), and strong antioxidant properties. The FRAP method measured 57.15 μmol ascorbic acid equivalents (AAE)/g dw, while the DPPH radical scavenging activity method measured 47.55 μmol AAE/g dw. This study was carried out to evaluate and improve the concentration of bioactive compounds in <i>N. officinale</i> leaf extract, resulting in a product with multiple applications across the food, cosmetic, and pharmaceutical industries.
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spelling doaj-art-e9c1d8ec3d5e43cf8dce1199c62405b82025-08-20T01:53:49ZengMDPI AGApplied Sciences2076-34172024-11-0114221073910.3390/app142210739The Value of Using Green Extraction Techniques to Enhance Polyphenol Content and Antioxidant Activity in <i>Nasturtium officinale</i> LeavesEva Naoum0Aikaterini Xynopoulou1Konstantina Kotsou2Theodoros Chatzimitakos3Vassilis Athanasiadis4Eleni Bozinou5Stavros I. Lalas6Department of Food Science and Nutrition, University of Thessaly, Terma N. Temponera Str., 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, Terma N. Temponera Str., 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, Terma N. Temponera Str., 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, Terma N. Temponera Str., 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, Terma N. Temponera Str., 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, Terma N. Temponera Str., 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, Terma N. Temponera Str., 43100 Karditsa, GreeceIncreasing research is being directed toward the production of value-added products using plant extracts that are super-fortified with antioxidants. In this study, the extraction parameters for bioactive compounds (such as polyphenols) from <i>Nasturtium officinale</i> leaves and their antioxidant properties were optimized using response surface methodology. The optimization procedure examined the effects of the extraction temperature, time, and solvent composition on conventional magnetic stirring (ST). In addition, the impacts of two green techniques—pulsed electric field (PEF) and ultrasound (US)—were evaluated individually and in combination to assess their potential to enhance the extraction of the compounds. According to our findings, under the proposed extraction conditions (a combination of PEF, US, and ST as a extraction technique, 50% ethanolic solvent, for 30 min at 80 °C). <i>N. officinale</i> leaf extract proved to be an excellent source of bioactive compounds, with extracts containing rosmarinic acid (3.42 mg/g dried weight (dw)), chlorogenic acid (3.13 mg/g dw), total polyphenol content (28.82 mg of gallic acid equivalents (GAE)/g dw), and strong antioxidant properties. The FRAP method measured 57.15 μmol ascorbic acid equivalents (AAE)/g dw, while the DPPH radical scavenging activity method measured 47.55 μmol AAE/g dw. This study was carried out to evaluate and improve the concentration of bioactive compounds in <i>N. officinale</i> leaf extract, resulting in a product with multiple applications across the food, cosmetic, and pharmaceutical industries.https://www.mdpi.com/2076-3417/14/22/10739watercressgreen extraction techniquespulsed electric fieldultrasoundpolyphenolsrosmarinic acid
spellingShingle Eva Naoum
Aikaterini Xynopoulou
Konstantina Kotsou
Theodoros Chatzimitakos
Vassilis Athanasiadis
Eleni Bozinou
Stavros I. Lalas
The Value of Using Green Extraction Techniques to Enhance Polyphenol Content and Antioxidant Activity in <i>Nasturtium officinale</i> Leaves
Applied Sciences
watercress
green extraction techniques
pulsed electric field
ultrasound
polyphenols
rosmarinic acid
title The Value of Using Green Extraction Techniques to Enhance Polyphenol Content and Antioxidant Activity in <i>Nasturtium officinale</i> Leaves
title_full The Value of Using Green Extraction Techniques to Enhance Polyphenol Content and Antioxidant Activity in <i>Nasturtium officinale</i> Leaves
title_fullStr The Value of Using Green Extraction Techniques to Enhance Polyphenol Content and Antioxidant Activity in <i>Nasturtium officinale</i> Leaves
title_full_unstemmed The Value of Using Green Extraction Techniques to Enhance Polyphenol Content and Antioxidant Activity in <i>Nasturtium officinale</i> Leaves
title_short The Value of Using Green Extraction Techniques to Enhance Polyphenol Content and Antioxidant Activity in <i>Nasturtium officinale</i> Leaves
title_sort value of using green extraction techniques to enhance polyphenol content and antioxidant activity in i nasturtium officinale i leaves
topic watercress
green extraction techniques
pulsed electric field
ultrasound
polyphenols
rosmarinic acid
url https://www.mdpi.com/2076-3417/14/22/10739
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