Biopharmaceutical profiling of anti-infective sanggenons from Morus alba root bark for inhalation administration

Biopharmaceutical profiling of anti-infective sanggenons from Morus alba root bark for inhalation administration

Mulberry Diels-Alder-type adducts (MDAAs), isolated from Morus alba root bark, exhibit dual activity against viral and bacterial pathogens but show sobering efficacy following oral administration. Inhalation administration may overcome issues with oral bioavailability and improve efficacy for the tr...

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Bibliographic Details
Main Authors: Jacqueline Schwarzinger, Sigrid Adelsberger, Karin Ortmayr, Sarah Luise Stellnberger, Ammar Tahir, Gabriela Hädrich, Verena Pichler, Judith M. Rollinger, Ulrike Grienke, Lea Ann Dailey
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Morus alba
Moraceae
Inhalation
Biopharmaceutical profiling
Pharmacokinetic synergy
Permeability
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156724000446
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