Inflammatory links between epilepsy and depression: a review of mechanisms and therapeutic strategies

Depression is the most common psychiatric comorbidity of epilepsy. While antiseizure medications (ASMs) can exacerbate depressive symptoms, depression itself may increase both the frequency and duration of epileptic seizures. The pathophysiological mechanisms underlying epilepsy-depression comorbidi...

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Bibliographic Details
Main Authors: Yu-Qian Shi, He-Cai Yang, Cong He, Yu-Hao Wang, Jia Zheng, Xing-Yi Wang, Fang-Yi Hao, Chu-Wen Feng, Lin Ma, Yue-Hui Zhang, Zheng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1614297/full
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