SNX10 Is Involved in Ovarian Cancer Cell Metastasis by Repolarizing Tumor-Associated Macrophages Through mTOR1/Lysosomes Pathway

SNX10 Is Involved in Ovarian Cancer Cell Metastasis by Repolarizing Tumor-Associated Macrophages Through mTOR1/Lysosomes Pathway

<b>Background:</b> Tumor-associated macrophages (TAMs) are prevalent in advanced ovarian cancer tissues and ascites, significantly influencing disease prognosis. However, the mechanisms driving TAM polarization and their tumor-promoting effects remain poorly understood. <b>Methods&...

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Bibliographic Details
Main Authors: Ranran Chai, Kewei Zheng, Ting Xu, Hui Wang, Xiaobo Cheng, Chong Lu, Yu Kang
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomedicines
Subjects:
ovarian cancer
tumor associated macrophages
SNX10
lysosome
mTOR1
Online Access:https://www.mdpi.com/2227-9059/13/5/1021
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