Experiences of Patients and Families Living with Krabbe Disease

The challenges faced by patients with Krabbe disease remain unelucidated. This study aimed to identify these challenges and facilitate the development of methods for assessing the quality of life. This qualitative descriptive study used in-person or online semistructured interviews from March to Dec...

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Main Authors: Yuta Koto PhD, Wakana Yamashita MSN, Kumiko Kitamura MSN, Norio Sakai PhD
Format: Article
Language:English
Published: SAGE Publishing 2025-01-01
Series:Journal of Patient Experience
Online Access:https://doi.org/10.1177/23743735241309470
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author Yuta Koto PhD
Wakana Yamashita MSN
Kumiko Kitamura MSN
Norio Sakai PhD
author_facet Yuta Koto PhD
Wakana Yamashita MSN
Kumiko Kitamura MSN
Norio Sakai PhD
author_sort Yuta Koto PhD
collection DOAJ
description The challenges faced by patients with Krabbe disease remain unelucidated. This study aimed to identify these challenges and facilitate the development of methods for assessing the quality of life. This qualitative descriptive study used in-person or online semistructured interviews from March to December 2022 using a qualitative content analysis approach. Data were collected from one patient each for the late infantile, juvenile, and adult types of Krabbe disease. In total, 249 codes were extracted from the verbatim transcripts and integrated into 40 subcategories and eight categories. The categories were integrated into three themes: the impact of symptoms on daily life, challenges for healthcare systems, and challenges faced by family members. Patients experienced physical symptoms, social life challenges, and medical care difficulties. Additionally, families felt burdened caring for these patients. In conclusion, support systems for patients and their families during treatment and in their living environments should be developed to aid in managing these challenges. Moreover, a comprehensive scale that accurately reflects the social challenges faced by these patients and their families is needed.
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spelling doaj-art-e9b56304879342bd8a2246757d5282f52025-08-20T01:49:12ZengSAGE PublishingJournal of Patient Experience2374-37432025-01-011210.1177/23743735241309470Experiences of Patients and Families Living with Krabbe DiseaseYuta Koto PhD0Wakana Yamashita MSN1Kumiko Kitamura MSN2Norio Sakai PhD3 Faculty of Nursing, Graduate School of Nursing, , Hirakata, Japan Department of Clinical Genomics, , Irumagun, Japan Division of Health Science, Child Healthcare and Genetic Science Laboratory, , Suita, Japan Division of Health Science, Child Healthcare and Genetic Science Laboratory, , Suita, JapanThe challenges faced by patients with Krabbe disease remain unelucidated. This study aimed to identify these challenges and facilitate the development of methods for assessing the quality of life. This qualitative descriptive study used in-person or online semistructured interviews from March to December 2022 using a qualitative content analysis approach. Data were collected from one patient each for the late infantile, juvenile, and adult types of Krabbe disease. In total, 249 codes were extracted from the verbatim transcripts and integrated into 40 subcategories and eight categories. The categories were integrated into three themes: the impact of symptoms on daily life, challenges for healthcare systems, and challenges faced by family members. Patients experienced physical symptoms, social life challenges, and medical care difficulties. Additionally, families felt burdened caring for these patients. In conclusion, support systems for patients and their families during treatment and in their living environments should be developed to aid in managing these challenges. Moreover, a comprehensive scale that accurately reflects the social challenges faced by these patients and their families is needed.https://doi.org/10.1177/23743735241309470
spellingShingle Yuta Koto PhD
Wakana Yamashita MSN
Kumiko Kitamura MSN
Norio Sakai PhD
Experiences of Patients and Families Living with Krabbe Disease
Journal of Patient Experience
title Experiences of Patients and Families Living with Krabbe Disease
title_full Experiences of Patients and Families Living with Krabbe Disease
title_fullStr Experiences of Patients and Families Living with Krabbe Disease
title_full_unstemmed Experiences of Patients and Families Living with Krabbe Disease
title_short Experiences of Patients and Families Living with Krabbe Disease
title_sort experiences of patients and families living with krabbe disease
url https://doi.org/10.1177/23743735241309470
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