Covalent Affibody‐Molecular Glue Drug Conjugate Nanoagent for Proximity‐Enabled Reactive Therapeutics

Covalent Affibody‐Molecular Glue Drug Conjugate Nanoagent for Proximity‐Enabled Reactive Therapeutics

Abstract Sulfur‐fluoride exchange (SuFEx) reaction is an emerging class of click chemistry reaction. Owing to its efficient reactivity under physiological conditions, SuFEx reaction is used to construct covalent protein drugs. Herein, a covalent affibody‐molecular glue drug conjugate nanoagent is re...

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Bibliographic Details
Main Authors:	Wenhui Gao, Xiaoyuan Yang, Qingrong Li, Yingchun Liu, Wei Huang, Xuelin Xia, Deyue Yan
Format:	Article
Language:	English
Published:	Wiley 2025-03-01
Series:	Advanced Science
Subjects:	affibody‐molecular glue drug conjugate covalent nanoagent proximity‐enabled reactive therapeutics SuFEx reaction
Online Access:	https://doi.org/10.1002/advs.202412273
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