Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study Protocol

Introduction: In Ayurveda, Basti, or medicated enema, is recognised as a crucial component of Panchakarma, constituting half of the therapeutic approach. Matra Basti, a specific form of Basti Karma, is particularly effective in addressing disorders related to the nervous system, neuromuscular condit...

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Main Authors: Anil Ambadas Bhawade, Shweta Dadarao Parwe
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2025-06-01
Series:Journal of Clinical and Diagnostic Research
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Online Access:https://jcdr.net/articles/PDF/21066/68788_CE[Ra1]__F(IS)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdf
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author Anil Ambadas Bhawade
Shweta Dadarao Parwe
author_facet Anil Ambadas Bhawade
Shweta Dadarao Parwe
author_sort Anil Ambadas Bhawade
collection DOAJ
description Introduction: In Ayurveda, Basti, or medicated enema, is recognised as a crucial component of Panchakarma, constituting half of the therapeutic approach. Matra Basti, a specific form of Basti Karma, is particularly effective in addressing disorders related to the nervous system, neuromuscular conditions and nutritional imbalances. Gridhrasi, commonly known as sciatica, is characterised by pain that extends from the lower back to the legs. These conditions frequently develop due to a variety of factors, such as poor sitting posture, excessive physical strain and a sedentary lifestyle. Need of the study: In Ayurvedic practice, different medicated oils are prescribed based on the patient and the specific disease condition. Both Vajigandhadi oil and Sahacharadi oil are Ayurvedic formulations recommended for the treatment of Gridhrasi (sciatica) through per rectal administration. However, the comparative efficacy of these two oils in alleviating sciatic pain remains unclear. To address this knowledge gap, the present study will be conducted. Aim: To compare the efficacy of Vajigandhadi taila matrabasti (a form of unctuous enema) with Sahacharadi taila matrabasti (another form of unctuous enema) for the management of Gridhrasi (sciatica). Materials and Methods: A randomised controlled clinical trial will be conducted at MG Ayurved College, Hospital and Research Centre located in Salod (H), District Wardha, Maharashtra, India, from December 2022 to December 2025. In this study, a total of 80 participants will be randomly assigned to two groups, each consisting of 40 patients. Participants in group A will receive a Vajigandhadi taila matrabasti (a type of unctuous enema) at a dosage of 72 mL, administered rectally after meals for 14 days. Conversely, group-B will receive a Sahacharadi taila matrabasti (an unctuous enema) at the same dosage and administration schedule. Parameters will be assessed on the initial day, the 14th day and again after 30 days for follow-up purposes. Statistical analysis will be conducted using R (version 4.3.2) software. Objective parameters will be analysed using Independent t-tests, while subjective parameters will be analysed using Chi-square tests. Results will be presented as mean and standard deviation, with statistical significance at p-value <0.05.
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spelling doaj-art-e9b2c465b78e402eb946ac9d312ac7322025-08-20T02:02:13ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-06-01196JK01JK0410.7860/JCDR/2025/68788.21066Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study ProtocolAnil Ambadas Bhawade0Shweta Dadarao Parwe1PhD Scholar, Department of Panchakarma, Mahatma Gandhi Ayurved College Hospital and Research Centre, Salod (H), Datta Meghe Institute of Higher Education and Research (DMIHER) (Deemed to be University), Wardha, Maharashtra, India.Professor, Department of Panchakarma, Mahatma Gandhi Ayurved College Hospital and Research Centre, Salod (H), Datta Meghe Institute of Higher Education and Research (DMIHER) (Deemed to be University), Wardha, Maharashtra, India.Introduction: In Ayurveda, Basti, or medicated enema, is recognised as a crucial component of Panchakarma, constituting half of the therapeutic approach. Matra Basti, a specific form of Basti Karma, is particularly effective in addressing disorders related to the nervous system, neuromuscular conditions and nutritional imbalances. Gridhrasi, commonly known as sciatica, is characterised by pain that extends from the lower back to the legs. These conditions frequently develop due to a variety of factors, such as poor sitting posture, excessive physical strain and a sedentary lifestyle. Need of the study: In Ayurvedic practice, different medicated oils are prescribed based on the patient and the specific disease condition. Both Vajigandhadi oil and Sahacharadi oil are Ayurvedic formulations recommended for the treatment of Gridhrasi (sciatica) through per rectal administration. However, the comparative efficacy of these two oils in alleviating sciatic pain remains unclear. To address this knowledge gap, the present study will be conducted. Aim: To compare the efficacy of Vajigandhadi taila matrabasti (a form of unctuous enema) with Sahacharadi taila matrabasti (another form of unctuous enema) for the management of Gridhrasi (sciatica). Materials and Methods: A randomised controlled clinical trial will be conducted at MG Ayurved College, Hospital and Research Centre located in Salod (H), District Wardha, Maharashtra, India, from December 2022 to December 2025. In this study, a total of 80 participants will be randomly assigned to two groups, each consisting of 40 patients. Participants in group A will receive a Vajigandhadi taila matrabasti (a type of unctuous enema) at a dosage of 72 mL, administered rectally after meals for 14 days. Conversely, group-B will receive a Sahacharadi taila matrabasti (an unctuous enema) at the same dosage and administration schedule. Parameters will be assessed on the initial day, the 14th day and again after 30 days for follow-up purposes. Statistical analysis will be conducted using R (version 4.3.2) software. Objective parameters will be analysed using Independent t-tests, while subjective parameters will be analysed using Chi-square tests. Results will be presented as mean and standard deviation, with statistical significance at p-value <0.05.https://jcdr.net/articles/PDF/21066/68788_CE[Ra1]__F(IS)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdfbastipainrectal enemasciatic nerve
spellingShingle Anil Ambadas Bhawade
Shweta Dadarao Parwe
Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study Protocol
Journal of Clinical and Diagnostic Research
basti
pain
rectal enema
sciatic nerve
title Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study Protocol
title_full Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study Protocol
title_fullStr Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study Protocol
title_full_unstemmed Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study Protocol
title_short Clinical Evaluation of Vajigandhadi taila matrabasti versus Sahacharadi taila matrabasti in the Management of Gridhrasi (Sciatica): A Study Protocol
title_sort clinical evaluation of vajigandhadi taila matrabasti versus sahacharadi taila matrabasti in the management of gridhrasi sciatica a study protocol
topic basti
pain
rectal enema
sciatic nerve
url https://jcdr.net/articles/PDF/21066/68788_CE[Ra1]__F(IS)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdf
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