Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography
Introduction and Objectives: Controlled attenuation parameter (CAP) has been developed as a non-invasive method for detecting liver steatosis. The aim of the study was to determine factors associated with non-obtaining lower IQR-CAP values. Materials and Methods: Retrospective revision of medical re...
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Elsevier
2025-01-01
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| Series: | Annals of Hepatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268124005453 |
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| author | Iván López-Mendez Juan Luis Romero-Flores Graciela Castro-Narro Misael Uribe Eva Juárez-Hernández |
| author_facet | Iván López-Mendez Juan Luis Romero-Flores Graciela Castro-Narro Misael Uribe Eva Juárez-Hernández |
| author_sort | Iván López-Mendez |
| collection | DOAJ |
| description | Introduction and Objectives: Controlled attenuation parameter (CAP) has been developed as a non-invasive method for detecting liver steatosis. The aim of the study was to determine factors associated with non-obtaining lower IQR-CAP values. Materials and Methods: Retrospective revision of medical records of CAP studies for steatosis screening. Anthropometrical, biochemical, and quality variables were collected. A logistic regression analysis was performed to determine independent associations with non-obtaining IQR-CAP <30, <20, and <10 in all patients and then adjusted for obesity/overweight and severity of steatosis. Results: 5061 studies were analyzed. Median IQR-CAP was 26 [IQR 20–33] dB/m. Steatosis prevalence was 39.4 % (n = 1996). In overweight patients, significant alcohol consumption was an independent factor for non-obtaining IQR-CAP <30; meanwhile, in obese patients glucose impairment, AST, skPa>8 and steatosis severity were independent factors for non-obtaining lower IQR-CAP values. According to steatosis severity, the presence of anthropometric characteristics of obesity and significant alcohol consumption were independent factors for non-obtaining lower IQR-CAP values. Conclusions: In steatosis detection by CAP, obesity, significant alcohol consumption, glucose impairments, and minimal liver function test alterations were independent factors associated with non-obtaining lower values of IQR-CAP. |
| format | Article |
| id | doaj-art-e9acec3f19df492dbb8fb80c5cc6ddca |
| institution | Kabale University |
| issn | 1665-2681 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj-art-e9acec3f19df492dbb8fb80c5cc6ddca2024-12-18T08:47:39ZengElsevierAnnals of Hepatology1665-26812025-01-01301101762Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastographyIván López-Mendez0Juan Luis Romero-Flores1Graciela Castro-Narro2Misael Uribe3Eva Juárez-Hernández4Transplant and Hepatology Unit, Medica Sur Clinic & Foundation, Mexico City, Mexico; Corresponding authors.Gastroenterology and Obesity Unit, Medica Sur Clinic & Foundation, Mexico City, MexicoTransplant and Hepatology Unit, Medica Sur Clinic & Foundation, Mexico City, MexicoGastroenterology and Obesity Unit, Medica Sur Clinic & Foundation, Mexico City, MexicoTranslational Research Unit, Medica Sur Clinic & Foundation, Mexico City, Mexico; Corresponding authors.Introduction and Objectives: Controlled attenuation parameter (CAP) has been developed as a non-invasive method for detecting liver steatosis. The aim of the study was to determine factors associated with non-obtaining lower IQR-CAP values. Materials and Methods: Retrospective revision of medical records of CAP studies for steatosis screening. Anthropometrical, biochemical, and quality variables were collected. A logistic regression analysis was performed to determine independent associations with non-obtaining IQR-CAP <30, <20, and <10 in all patients and then adjusted for obesity/overweight and severity of steatosis. Results: 5061 studies were analyzed. Median IQR-CAP was 26 [IQR 20–33] dB/m. Steatosis prevalence was 39.4 % (n = 1996). In overweight patients, significant alcohol consumption was an independent factor for non-obtaining IQR-CAP <30; meanwhile, in obese patients glucose impairment, AST, skPa>8 and steatosis severity were independent factors for non-obtaining lower IQR-CAP values. According to steatosis severity, the presence of anthropometric characteristics of obesity and significant alcohol consumption were independent factors for non-obtaining lower IQR-CAP values. Conclusions: In steatosis detection by CAP, obesity, significant alcohol consumption, glucose impairments, and minimal liver function test alterations were independent factors associated with non-obtaining lower values of IQR-CAP.http://www.sciencedirect.com/science/article/pii/S1665268124005453SteatosisReliabilityTransient elastographyObesity |
| spellingShingle | Iván López-Mendez Juan Luis Romero-Flores Graciela Castro-Narro Misael Uribe Eva Juárez-Hernández Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography Annals of Hepatology Steatosis Reliability Transient elastography Obesity |
| title | Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography |
| title_full | Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography |
| title_fullStr | Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography |
| title_full_unstemmed | Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography |
| title_short | Factors associated with obtaining lower IQR-CAP values in the detection of hepatic steatosis by transient elastography |
| title_sort | factors associated with obtaining lower iqr cap values in the detection of hepatic steatosis by transient elastography |
| topic | Steatosis Reliability Transient elastography Obesity |
| url | http://www.sciencedirect.com/science/article/pii/S1665268124005453 |
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