Combining experiment and prediction to explore surface chemistry and dissolution
A crystal structure is often an integral component in the development of a new pharmaceutical product, and these structures are frequently used to understand, assess and often predict both the manufacturing and in vivo behaviour of these compounds. Combining a range of analytical methods with comput...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2025-03-01
|
| Series: | IUCrJ |
| Subjects: | |
| Online Access: | https://journals.iucr.org/paper?S2052252525001782 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850236370078924800 |
|---|---|
| author | Andrew G. P. Maloney |
| author_facet | Andrew G. P. Maloney |
| author_sort | Andrew G. P. Maloney |
| collection | DOAJ |
| description | A crystal structure is often an integral component in the development of a new pharmaceutical product, and these structures are frequently used to understand, assess and often predict both the manufacturing and in vivo behaviour of these compounds. Combining a range of analytical methods with computational analysis of the crystal surfaces, Zmeškalová et al. [(2025). IUCrJ, 12, 141–154] link the properties of three solid forms of a biologically active molecule to its dissolution behaviour. |
| format | Article |
| id | doaj-art-e9acc4ded9f34a5fb002eff6517a4b4b |
| institution | OA Journals |
| issn | 2052-2525 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | IUCrJ |
| spelling | doaj-art-e9acc4ded9f34a5fb002eff6517a4b4b2025-08-20T02:01:58ZengInternational Union of CrystallographyIUCrJ2052-25252025-03-0112213713810.1107/S2052252525001782me6321Combining experiment and prediction to explore surface chemistry and dissolutionAndrew G. P. Maloney0The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, United KingdomA crystal structure is often an integral component in the development of a new pharmaceutical product, and these structures are frequently used to understand, assess and often predict both the manufacturing and in vivo behaviour of these compounds. Combining a range of analytical methods with computational analysis of the crystal surfaces, Zmeškalová et al. [(2025). IUCrJ, 12, 141–154] link the properties of three solid forms of a biologically active molecule to its dissolution behaviour.https://journals.iucr.org/paper?S2052252525001782crystal surfacespharmaceuticalsparticle shapecsd-particledissolution |
| spellingShingle | Andrew G. P. Maloney Combining experiment and prediction to explore surface chemistry and dissolution IUCrJ crystal surfaces pharmaceuticals particle shape csd-particle dissolution |
| title | Combining experiment and prediction to explore surface chemistry and dissolution |
| title_full | Combining experiment and prediction to explore surface chemistry and dissolution |
| title_fullStr | Combining experiment and prediction to explore surface chemistry and dissolution |
| title_full_unstemmed | Combining experiment and prediction to explore surface chemistry and dissolution |
| title_short | Combining experiment and prediction to explore surface chemistry and dissolution |
| title_sort | combining experiment and prediction to explore surface chemistry and dissolution |
| topic | crystal surfaces pharmaceuticals particle shape csd-particle dissolution |
| url | https://journals.iucr.org/paper?S2052252525001782 |
| work_keys_str_mv | AT andrewgpmaloney combiningexperimentandpredictiontoexploresurfacechemistryanddissolution |