Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique

Abstract Identification of infected lesions in chronic haematogenous osteomyelitis (CHOM) is challenging due to no distinct boundary. The optimal methods of debridement and bone reconstruction remain controversial. The aim of this study was to evaluate the clinical efficacy of selective segmental os...

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Main Authors: Yi Wang, Junyi Li, Xijiao Zhang, Xiaoyong Yang, Muguo Song, Kehan Lv, Yongqing Xu, Jian Shi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Surgery
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Online Access:https://doi.org/10.1186/s12893-025-02865-1
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author Yi Wang
Junyi Li
Xijiao Zhang
Xiaoyong Yang
Muguo Song
Kehan Lv
Yongqing Xu
Jian Shi
author_facet Yi Wang
Junyi Li
Xijiao Zhang
Xiaoyong Yang
Muguo Song
Kehan Lv
Yongqing Xu
Jian Shi
author_sort Yi Wang
collection DOAJ
description Abstract Identification of infected lesions in chronic haematogenous osteomyelitis (CHOM) is challenging due to no distinct boundary. The optimal methods of debridement and bone reconstruction remain controversial. The aim of this study was to evaluate the clinical efficacy of selective segmental osteotomy with induced membrane technique in adult CHOM patients of the femur or tibia. The patients who underwent a staged surgery of induced membrane technique were include. In the first stage. the patients were treated by selective segmental osteotomy for debridement according to imaging result preoperatively. In the second stage, spacer removing, fixation and bone grafting were performed sequentially. 16 patients were included. The mean age was 34.7 years. After debridement, the mean bone defects length was 7.9 cm. At a mean followed-up of 30.5 months, no infection recurrence in all patients. At the last follow-up, all patients achieved bone union on average at 6.9 months. Visual Analogue Scale (VAS) score, Self-rated Anxiety Scale (SAS) score, and Hospital for Special Surgery (HSS) score improved at 3 months after the second stage of surgery and at the final follow-up compared with initial admission (P < 0.05). For adult patients with CHOM of femur and tibia, selective segmental osteotomy with induced membrane technique is a feasible and effective treatment method.
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spelling doaj-art-e9aab8410e08419981ddea2e4b7f02c72025-08-20T03:04:58ZengBMCBMC Surgery1471-24822025-04-012511810.1186/s12893-025-02865-1Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane techniqueYi Wang0Junyi Li1Xijiao Zhang2Xiaoyong Yang3Muguo Song4Kehan Lv5Yongqing Xu6Jian Shi7Department of Orthopaedics, 920th Hospital of the Joint Logistics Support Force of the PLADepartment of Orthopaedics, 920th Hospital of the Joint Logistics Support Force of the PLADepartment of Orthopaedics, 920th Hospital of the Joint Logistics Support Force of the PLADepartment of Orthopaedics, 920th Hospital of the Joint Logistics Support Force of the PLADepartment of Orthopaedics, 920th Hospital of the Joint Logistics Support Force of the PLADepartment of Orthopaedics, 920th Hospital of the Joint Logistics Support Force of the PLADepartment of Orthopaedics, 920th Hospital of the Joint Logistics Support Force of the PLADepartment of Orthopaedics, 920th Hospital of the Joint Logistics Support Force of the PLAAbstract Identification of infected lesions in chronic haematogenous osteomyelitis (CHOM) is challenging due to no distinct boundary. The optimal methods of debridement and bone reconstruction remain controversial. The aim of this study was to evaluate the clinical efficacy of selective segmental osteotomy with induced membrane technique in adult CHOM patients of the femur or tibia. The patients who underwent a staged surgery of induced membrane technique were include. In the first stage. the patients were treated by selective segmental osteotomy for debridement according to imaging result preoperatively. In the second stage, spacer removing, fixation and bone grafting were performed sequentially. 16 patients were included. The mean age was 34.7 years. After debridement, the mean bone defects length was 7.9 cm. At a mean followed-up of 30.5 months, no infection recurrence in all patients. At the last follow-up, all patients achieved bone union on average at 6.9 months. Visual Analogue Scale (VAS) score, Self-rated Anxiety Scale (SAS) score, and Hospital for Special Surgery (HSS) score improved at 3 months after the second stage of surgery and at the final follow-up compared with initial admission (P < 0.05). For adult patients with CHOM of femur and tibia, selective segmental osteotomy with induced membrane technique is a feasible and effective treatment method.https://doi.org/10.1186/s12893-025-02865-1Chronic osteomyelitisFemurTibiaInduced membrane techniqueInternal fixation
spellingShingle Yi Wang
Junyi Li
Xijiao Zhang
Xiaoyong Yang
Muguo Song
Kehan Lv
Yongqing Xu
Jian Shi
Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique
BMC Surgery
Chronic osteomyelitis
Femur
Tibia
Induced membrane technique
Internal fixation
title Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique
title_full Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique
title_fullStr Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique
title_full_unstemmed Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique
title_short Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique
title_sort clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique
topic Chronic osteomyelitis
Femur
Tibia
Induced membrane technique
Internal fixation
url https://doi.org/10.1186/s12893-025-02865-1
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