Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children
Necrotizing enterocolitis is a multifactorial pathology with an unspecified pathogenesis. These factors significantly complicate the differential diagnosis, which affects timely therapy and prognosis of the disease. The interstitial protein that binds fatty acids is a specific marker of enterocyte d...
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| Format: | Article |
| Language: | Russian |
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Open Systems Publication
2021-06-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/188 |
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| author | I. A. Bavykina A. A. Berdnikov |
| author_facet | I. A. Bavykina A. A. Berdnikov |
| author_sort | I. A. Bavykina |
| collection | DOAJ |
| description | Necrotizing enterocolitis is a multifactorial pathology with an unspecified pathogenesis. These factors significantly complicate the differential diagnosis, which affects timely therapy and prognosis of the disease. The interstitial protein that binds fatty acids is a specific marker of enterocyte damage; however, the reference values have not yet been clarified. This marker has proven itself in pathologies such as celiac disease, purulent diseases and abdominal trauma, during abdominal operations and other pathologies accompanied by changes in the morphological and histological picture in the intestine. The article presents modern literature data on the diagnostic value of determining the level of protein that binds fatty acids as a marker of damage to enterocytes in necrotizing enterocolitis in children. The value is shown both for differential diagnostics and the prognostic value of an increase in the concentration of the marker in the blood or urine of patients. |
| format | Article |
| id | doaj-art-e9a99b7025f74c549814eab3ec66e651 |
| institution | Kabale University |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2021-06-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-e9a99b7025f74c549814eab3ec66e6512025-08-20T03:42:34ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-0109313310.26295/OS.2020.78.43.006187Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in childrenI. A. Bavykina0A. A. Berdnikov1The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian FederationBudgetary healthcare institution of the Voronezh region «Voronezh Regional Children’s Clinical Hospital No. 1»Necrotizing enterocolitis is a multifactorial pathology with an unspecified pathogenesis. These factors significantly complicate the differential diagnosis, which affects timely therapy and prognosis of the disease. The interstitial protein that binds fatty acids is a specific marker of enterocyte damage; however, the reference values have not yet been clarified. This marker has proven itself in pathologies such as celiac disease, purulent diseases and abdominal trauma, during abdominal operations and other pathologies accompanied by changes in the morphological and histological picture in the intestine. The article presents modern literature data on the diagnostic value of determining the level of protein that binds fatty acids as a marker of damage to enterocytes in necrotizing enterocolitis in children. The value is shown both for differential diagnostics and the prognostic value of an increase in the concentration of the marker in the blood or urine of patients.https://journal.lvrach.ru/jour/article/view/188enterocytesnecrotizing enterocolitischildrenintestines |
| spellingShingle | I. A. Bavykina A. A. Berdnikov Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children Лечащий Врач enterocytes necrotizing enterocolitis children intestines |
| title | Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children |
| title_full | Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children |
| title_fullStr | Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children |
| title_full_unstemmed | Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children |
| title_short | Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children |
| title_sort | interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children |
| topic | enterocytes necrotizing enterocolitis children intestines |
| url | https://journal.lvrach.ru/jour/article/view/188 |
| work_keys_str_mv | AT iabavykina interstitialproteinthatbindsfattyacidsinthediagnosisofnecrotizingenterocolitisinchildren AT aaberdnikov interstitialproteinthatbindsfattyacidsinthediagnosisofnecrotizingenterocolitisinchildren |