Interstitial protein that binds fatty acids in the diagnosis of necrotizing enterocolitis in children
Necrotizing enterocolitis is a multifactorial pathology with an unspecified pathogenesis. These factors significantly complicate the differential diagnosis, which affects timely therapy and prognosis of the disease. The interstitial protein that binds fatty acids is a specific marker of enterocyte d...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Open Systems Publication
2021-06-01
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| Series: | Лечащий Врач |
| Subjects: | |
| Online Access: | https://journal.lvrach.ru/jour/article/view/188 |
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| Summary: | Necrotizing enterocolitis is a multifactorial pathology with an unspecified pathogenesis. These factors significantly complicate the differential diagnosis, which affects timely therapy and prognosis of the disease. The interstitial protein that binds fatty acids is a specific marker of enterocyte damage; however, the reference values have not yet been clarified. This marker has proven itself in pathologies such as celiac disease, purulent diseases and abdominal trauma, during abdominal operations and other pathologies accompanied by changes in the morphological and histological picture in the intestine. The article presents modern literature data on the diagnostic value of determining the level of protein that binds fatty acids as a marker of damage to enterocytes in necrotizing enterocolitis in children. The value is shown both for differential diagnostics and the prognostic value of an increase in the concentration of the marker in the blood or urine of patients. |
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| ISSN: | 1560-5175 2687-1181 |