A prebiotic dietary pilot intervention restores faecal metabolites and may be neuroprotective in Parkinson’s Disease

A prebiotic dietary pilot intervention restores faecal metabolites and may be neuroprotective in Parkinson’s Disease

Abstract Current treatment of Parkinson’s Disease (PD) remains symptomatic, and disease-modifying approaches are urgently required. A promising approach is to modify intestinal microbiota and key metabolites of bacterial fermentation: short-chain fatty acids (SCFA), which are decreased in PD. A pros...

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Main Authors: Janis Rebecca Bedarf, Stefano Romano, Silke Sophie Heinzmann, Anthony Duncan, Maria H. Traka, Duncan Ng, Daniella Segovia-Lizano, Marie-Christine Simon, Arjan Narbad, Ullrich Wüllner, Falk Hildebrand
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00885-5
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