Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase report
Thyroid carcinoma with thymus-like differentiation (Carcinoma Showing Thymus-Like Differentiation, CASTLE) is an extremely rare disease. It arises from the thymus tissue ectopic into the tissue of the thyroid gland, usually in patients 40–50 years old. In this work, we present an observation of the...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2021-08-01
|
| Series: | Опухоли головы и шеи |
| Subjects: | |
| Online Access: | https://ogsh.abvpress.ru/jour/article/view/649 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849242475353341952 |
|---|---|
| author | A. A. Ilyin V. V. Polkin P. A. Isaev F. E. Sevrukov N. Yu. Dvinskych M. I. Ryzhenkova S. A. Ivanov A. D. Kaprin |
| author_facet | A. A. Ilyin V. V. Polkin P. A. Isaev F. E. Sevrukov N. Yu. Dvinskych M. I. Ryzhenkova S. A. Ivanov A. D. Kaprin |
| author_sort | A. A. Ilyin |
| collection | DOAJ |
| description | Thyroid carcinoma with thymus-like differentiation (Carcinoma Showing Thymus-Like Differentiation, CASTLE) is an extremely rare disease. It arises from the thymus tissue ectopic into the tissue of the thyroid gland, usually in patients 40–50 years old. In this work, we present an observation of the development of CASTLE in a patient at a young age. A 21-year-old woman was admitted to our clinic with a volumetric education in the projection of the left lobe of the thyroid gland. Ultrasound revealed a 5-centimeter thyroid tumor. Surgery was performed in the scope of thyroidectomy, selective cervical dissection (level VI). Morphological and immunohistochemical studies showed that cancer has a thymus-like differentiation (CASTLE). After 32 months, she recurred to the lymph nodes of the neck (level IV on the left). She underwent repeated surgery, after which she was observed without signs of relapse for 120 months. The rarity of the pathology leads to difficulties in establishing a diagnosis at the preoperative stage and in choosing the optimal treatment tactics during treatment and further follow-up. |
| format | Article |
| id | doaj-art-e99afb166d8241cc8d962ee3a1918c17 |
| institution | Kabale University |
| issn | 2222-1468 2411-4634 |
| language | Russian |
| publishDate | 2021-08-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли головы и шеи |
| spelling | doaj-art-e99afb166d8241cc8d962ee3a1918c172025-08-20T03:59:48ZrusABV-pressОпухоли головы и шеи2222-14682411-46342021-08-01112647110.17650/2222-1468-2021-11-2-64-71448Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase reportA. A. Ilyin0V. V. Polkin1P. A. Isaev2F. E. Sevrukov3N. Yu. Dvinskych4M. I. Ryzhenkova5S. A. Ivanov6A. D. Kaprin7A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of RussiaA.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of RussiaNational Medical Research Radiological Center, Ministry of Health of RussiaThyroid carcinoma with thymus-like differentiation (Carcinoma Showing Thymus-Like Differentiation, CASTLE) is an extremely rare disease. It arises from the thymus tissue ectopic into the tissue of the thyroid gland, usually in patients 40–50 years old. In this work, we present an observation of the development of CASTLE in a patient at a young age. A 21-year-old woman was admitted to our clinic with a volumetric education in the projection of the left lobe of the thyroid gland. Ultrasound revealed a 5-centimeter thyroid tumor. Surgery was performed in the scope of thyroidectomy, selective cervical dissection (level VI). Morphological and immunohistochemical studies showed that cancer has a thymus-like differentiation (CASTLE). After 32 months, she recurred to the lymph nodes of the neck (level IV on the left). She underwent repeated surgery, after which she was observed without signs of relapse for 120 months. The rarity of the pathology leads to difficulties in establishing a diagnosis at the preoperative stage and in choosing the optimal treatment tactics during treatment and further follow-up.https://ogsh.abvpress.ru/jour/article/view/649carcinomathyroid glandthymus-like differentiationcarcinoma showing tymus-like differentiation |
| spellingShingle | A. A. Ilyin V. V. Polkin P. A. Isaev F. E. Sevrukov N. Yu. Dvinskych M. I. Ryzhenkova S. A. Ivanov A. D. Kaprin Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase report Опухоли головы и шеи carcinoma thyroid gland thymus-like differentiation carcinoma showing tymus-like differentiation |
| title | Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase report |
| title_full | Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase report |
| title_fullStr | Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase report |
| title_full_unstemmed | Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase report |
| title_short | Thyroid carcinoma with thymus-like differentiation (CASTLE) tumor: а сase report |
| title_sort | thyroid carcinoma with thymus like differentiation castle tumor а сase report |
| topic | carcinoma thyroid gland thymus-like differentiation carcinoma showing tymus-like differentiation |
| url | https://ogsh.abvpress.ru/jour/article/view/649 |
| work_keys_str_mv | AT aailyin thyroidcarcinomawiththymuslikedifferentiationcastletumorasasereport AT vvpolkin thyroidcarcinomawiththymuslikedifferentiationcastletumorasasereport AT paisaev thyroidcarcinomawiththymuslikedifferentiationcastletumorasasereport AT fesevrukov thyroidcarcinomawiththymuslikedifferentiationcastletumorasasereport AT nyudvinskych thyroidcarcinomawiththymuslikedifferentiationcastletumorasasereport AT miryzhenkova thyroidcarcinomawiththymuslikedifferentiationcastletumorasasereport AT saivanov thyroidcarcinomawiththymuslikedifferentiationcastletumorasasereport AT adkaprin thyroidcarcinomawiththymuslikedifferentiationcastletumorasasereport |