Clinical observation of monoclonal fibrillary glomerulonephritis
Monoclonal gammopathy of renal significance is a condition caused by the proliferation of a clone of B-lymphocytes or plasma cells that does not reach the criteria required for the initiation of treatment for oncohematological indications, but is characterized by the secretion of nephrotoxic parapro...
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| Format: | Article |
| Language: | Russian |
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Private institution educational organization of higher education "Medical University "ReaViz"
2025-02-01
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| Series: | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
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| Online Access: | https://vestnik.reaviz.ru/jour/article/view/1123 |
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| _version_ | 1849402705476321280 |
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| author | T. A. Garkusha F. V. Alyab'ev T. A. Vdovik |
| author_facet | T. A. Garkusha F. V. Alyab'ev T. A. Vdovik |
| author_sort | T. A. Garkusha |
| collection | DOAJ |
| description | Monoclonal gammopathy of renal significance is a condition caused by the proliferation of a clone of B-lymphocytes or plasma cells that does not reach the criteria required for the initiation of treatment for oncohematological indications, but is characterized by the secretion of nephrotoxic paraprotein. There are many morphological variants of this disease and their diagnosis requires the use of additional research methods. This article presents a clinical observation of a 54-year-old patient admitted to the nephrology department with nephrotic syndrome. According to the results of nephrobiopsy, the patient was diagnosed with monoclonal fibrillary glomerulonephritis. Additional examination of the patient did not reveal signs of lymphoproliferative disease. |
| format | Article |
| id | doaj-art-e99ae2cdd7214a1699c6c65f68a01efa |
| institution | Kabale University |
| issn | 2226-762X 2782-1579 |
| language | Russian |
| publishDate | 2025-02-01 |
| publisher | Private institution educational organization of higher education "Medical University "ReaViz" |
| record_format | Article |
| series | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
| spelling | doaj-art-e99ae2cdd7214a1699c6c65f68a01efa2025-08-20T03:37:28ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792025-02-0114661010.20340/vmi-rvz.2024.6.MORPH.1660Clinical observation of monoclonal fibrillary glomerulonephritisT. A. Garkusha0F. V. Alyab'ev1T. A. Vdovik2Krasnoyarsk State Medical University named after Professor V. F. Voyno-Yasenetsky; Krasnoyarsk Regional Pathological Anatomy BureauKrasnoyarsk State Medical University named after Professor V. F. Voyno-YasenetskyKrasnoyarsk State Medical University named after Professor V. F. Voyno-YasenetskyMonoclonal gammopathy of renal significance is a condition caused by the proliferation of a clone of B-lymphocytes or plasma cells that does not reach the criteria required for the initiation of treatment for oncohematological indications, but is characterized by the secretion of nephrotoxic paraprotein. There are many morphological variants of this disease and their diagnosis requires the use of additional research methods. This article presents a clinical observation of a 54-year-old patient admitted to the nephrology department with nephrotic syndrome. According to the results of nephrobiopsy, the patient was diagnosed with monoclonal fibrillary glomerulonephritis. Additional examination of the patient did not reveal signs of lymphoproliferative disease.https://vestnik.reaviz.ru/jour/article/view/1123glomerulonephritismembranousparaproteinemiasbiopsyneedlefluorescent antibody techniquemicroscopyelectronnephrotic syndromeb-lymphocytesplasma cellsimmunohistochemistry |
| spellingShingle | T. A. Garkusha F. V. Alyab'ev T. A. Vdovik Clinical observation of monoclonal fibrillary glomerulonephritis Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье glomerulonephritis membranous paraproteinemias biopsy needle fluorescent antibody technique microscopy electron nephrotic syndrome b-lymphocytes plasma cells immunohistochemistry |
| title | Clinical observation of monoclonal fibrillary glomerulonephritis |
| title_full | Clinical observation of monoclonal fibrillary glomerulonephritis |
| title_fullStr | Clinical observation of monoclonal fibrillary glomerulonephritis |
| title_full_unstemmed | Clinical observation of monoclonal fibrillary glomerulonephritis |
| title_short | Clinical observation of monoclonal fibrillary glomerulonephritis |
| title_sort | clinical observation of monoclonal fibrillary glomerulonephritis |
| topic | glomerulonephritis membranous paraproteinemias biopsy needle fluorescent antibody technique microscopy electron nephrotic syndrome b-lymphocytes plasma cells immunohistochemistry |
| url | https://vestnik.reaviz.ru/jour/article/view/1123 |
| work_keys_str_mv | AT tagarkusha clinicalobservationofmonoclonalfibrillaryglomerulonephritis AT fvalyabev clinicalobservationofmonoclonalfibrillaryglomerulonephritis AT tavdovik clinicalobservationofmonoclonalfibrillaryglomerulonephritis |