The Current Landscape of Donation After Circulatory Death Heart Transplantation—Where Do We Stand?
The growing disparity between the demand for donor hearts and their availability has reignited interest in donation after circulatory death (DCD) heart transplantation. Historically, DCD heart transplantation has been overshadowed by donation after brain death (DBD) due to ethical and preservation c...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-04-01
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| Series: | Transplantology |
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| Online Access: | https://www.mdpi.com/2673-3943/6/2/11 |
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| author | Albert Dweck Korri S. Hershenhouse Mayuko Uehara Tadahisa Sugiura Brandon E. Ferrell |
| author_facet | Albert Dweck Korri S. Hershenhouse Mayuko Uehara Tadahisa Sugiura Brandon E. Ferrell |
| author_sort | Albert Dweck |
| collection | DOAJ |
| description | The growing disparity between the demand for donor hearts and their availability has reignited interest in donation after circulatory death (DCD) heart transplantation. Historically, DCD heart transplantation has been overshadowed by donation after brain death (DBD) due to ethical and preservation challenges. However, recent advancements in procurement techniques allow for evaluation of the donor heart and enable the broader utilization of DCD donors. While challenges remain, early outcomes suggest comparable survival rates between DCD and DBD heart transplantation. This review provides a comprehensive overview of the historical evolution, current practices, and future directions of DCD heart transplantation. Here, we emphasize its potential to expand the heart donor pool and alleviate the organ shortage crisis. |
| format | Article |
| id | doaj-art-e9997674d823477c9c858c2e20fc8dc0 |
| institution | Kabale University |
| issn | 2673-3943 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Transplantology |
| spelling | doaj-art-e9997674d823477c9c858c2e20fc8dc02025-08-20T03:29:38ZengMDPI AGTransplantology2673-39432025-04-01621110.3390/transplantology6020011The Current Landscape of Donation After Circulatory Death Heart Transplantation—Where Do We Stand?Albert Dweck0Korri S. Hershenhouse1Mayuko Uehara2Tadahisa Sugiura3Brandon E. Ferrell4Albert Einstein College of Medicine, Bronx, NY 10461, USAMontefiore Medical Center, Department of Cardiothoracic and Vascular Surgery, Bronx, NY 10467, USAMontefiore Medical Center, Department of Cardiothoracic and Vascular Surgery, Bronx, NY 10467, USAMontefiore Medical Center, Department of Cardiothoracic and Vascular Surgery, Bronx, NY 10467, USAMontefiore Medical Center, Department of Cardiothoracic and Vascular Surgery, Bronx, NY 10467, USAThe growing disparity between the demand for donor hearts and their availability has reignited interest in donation after circulatory death (DCD) heart transplantation. Historically, DCD heart transplantation has been overshadowed by donation after brain death (DBD) due to ethical and preservation challenges. However, recent advancements in procurement techniques allow for evaluation of the donor heart and enable the broader utilization of DCD donors. While challenges remain, early outcomes suggest comparable survival rates between DCD and DBD heart transplantation. This review provides a comprehensive overview of the historical evolution, current practices, and future directions of DCD heart transplantation. Here, we emphasize its potential to expand the heart donor pool and alleviate the organ shortage crisis.https://www.mdpi.com/2673-3943/6/2/11heart transplantationdonation after circulatory deathorgan preservationorthotopic heart transplantationprocurementnormothermic regional perfusion |
| spellingShingle | Albert Dweck Korri S. Hershenhouse Mayuko Uehara Tadahisa Sugiura Brandon E. Ferrell The Current Landscape of Donation After Circulatory Death Heart Transplantation—Where Do We Stand? Transplantology heart transplantation donation after circulatory death organ preservation orthotopic heart transplantation procurement normothermic regional perfusion |
| title | The Current Landscape of Donation After Circulatory Death Heart Transplantation—Where Do We Stand? |
| title_full | The Current Landscape of Donation After Circulatory Death Heart Transplantation—Where Do We Stand? |
| title_fullStr | The Current Landscape of Donation After Circulatory Death Heart Transplantation—Where Do We Stand? |
| title_full_unstemmed | The Current Landscape of Donation After Circulatory Death Heart Transplantation—Where Do We Stand? |
| title_short | The Current Landscape of Donation After Circulatory Death Heart Transplantation—Where Do We Stand? |
| title_sort | current landscape of donation after circulatory death heart transplantation where do we stand |
| topic | heart transplantation donation after circulatory death organ preservation orthotopic heart transplantation procurement normothermic regional perfusion |
| url | https://www.mdpi.com/2673-3943/6/2/11 |
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