NONINVASIVE EVALUATION OF FIBRINOLYTIC TREATMENT EFFICACY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION
Aim. To elaborate additional electrocardiographic (ECG) criteria for evaluation of the thrombolytic therapy (TLT) efficacy in patients with acute coronary syndrome (ACS) with ST segment elevation with discriminant model construction. Material and methods. TLT with streptokinase was performed in 123...
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Столичная издательская компания
2016-01-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/743 |
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| _version_ | 1849227906689007616 |
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| author | I. I. Shevchenko |
| author_facet | I. I. Shevchenko |
| author_sort | I. I. Shevchenko |
| collection | DOAJ |
| description | Aim. To elaborate additional electrocardiographic (ECG) criteria for evaluation of the thrombolytic therapy (TLT) efficacy in patients with acute coronary syndrome (ACS) with ST segment elevation with discriminant model construction. Material and methods. TLT with streptokinase was performed in 123 patients (108 men, 15 women) with ACS with ST segment elevation in the first 6 h after symptoms onset. Streptokinase i.v. infusion was performed in dose of 1.5 million IU. ECG was recorded at baseline and after TLT. Results. Additional ECG criteria for evaluation of TLT efficacy was elaborated in patients with ACS with ST segment elevation: sum of ST segment elevations in 12-lead; ratio of registered QT interval duration to proper corrected QT interval; corrected variance. Among 123 patients elaborated model was correct in 92.7% of cases. Conclusion. Elaborated discriminant model provides an opportunity to specify effective, uncertain and ineffective TLT within 3 h after TLT. |
| format | Article |
| id | doaj-art-e998d81800d047e09b6c935c6df4970f |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-e998d81800d047e09b6c935c6df4970f2025-08-23T10:00:22ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-017215115710.20996/1819-6446-2011-7-2-151-157742NONINVASIVE EVALUATION OF FIBRINOLYTIC TREATMENT EFFICACY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATIONI. I. Shevchenko0Municipal Emergency Care Hospital №10Aim. To elaborate additional electrocardiographic (ECG) criteria for evaluation of the thrombolytic therapy (TLT) efficacy in patients with acute coronary syndrome (ACS) with ST segment elevation with discriminant model construction. Material and methods. TLT with streptokinase was performed in 123 patients (108 men, 15 women) with ACS with ST segment elevation in the first 6 h after symptoms onset. Streptokinase i.v. infusion was performed in dose of 1.5 million IU. ECG was recorded at baseline and after TLT. Results. Additional ECG criteria for evaluation of TLT efficacy was elaborated in patients with ACS with ST segment elevation: sum of ST segment elevations in 12-lead; ratio of registered QT interval duration to proper corrected QT interval; corrected variance. Among 123 patients elaborated model was correct in 92.7% of cases. Conclusion. Elaborated discriminant model provides an opportunity to specify effective, uncertain and ineffective TLT within 3 h after TLT.https://www.rpcardio.online/jour/article/view/743fibrinolytic treatmentsum st segment elevationscorrect dispersion of qt intervaldiscriminant model |
| spellingShingle | I. I. Shevchenko NONINVASIVE EVALUATION OF FIBRINOLYTIC TREATMENT EFFICACY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION Рациональная фармакотерапия в кардиологии fibrinolytic treatment sum st segment elevations correct dispersion of qt interval discriminant model |
| title | NONINVASIVE EVALUATION OF FIBRINOLYTIC TREATMENT EFFICACY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION |
| title_full | NONINVASIVE EVALUATION OF FIBRINOLYTIC TREATMENT EFFICACY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION |
| title_fullStr | NONINVASIVE EVALUATION OF FIBRINOLYTIC TREATMENT EFFICACY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION |
| title_full_unstemmed | NONINVASIVE EVALUATION OF FIBRINOLYTIC TREATMENT EFFICACY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION |
| title_short | NONINVASIVE EVALUATION OF FIBRINOLYTIC TREATMENT EFFICACY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION |
| title_sort | noninvasive evaluation of fibrinolytic treatment efficacy in patients with acute coronary syndrome with st segment elevation |
| topic | fibrinolytic treatment sum st segment elevations correct dispersion of qt interval discriminant model |
| url | https://www.rpcardio.online/jour/article/view/743 |
| work_keys_str_mv | AT iishevchenko noninvasiveevaluationoffibrinolytictreatmentefficacyinpatientswithacutecoronarysyndromewithstsegmentelevation |