Leptin receptor polymorphism increases the risk of painful symptoms in Brazilian women with endometriosis

Leptin receptor polymorphism increases the risk of painful symptoms in Brazilian women with endometriosis

Abstract Objective: Endometriosis pain is associated with inflammatory cytokines, such as leptin (LEP), through activation with its receptor (LEPR), and its expression can be influenced by the presence of genetic polymorphisms. Therefore, this study aims to evaluate the role of the LEP rs7799039 an...

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Bibliographic Details
Main Authors: Jéssica Vilarinho Cardoso, Daniel Escorsim Machado, Fernanda Nunes de Almeida, Plínio Tostes Berardo, Rui Medeiros, Jamila Alessandra Perini
Format: Article
Language:English
Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia 2025-08-01
Series:Revista Brasileira de Ginecologia e Obstetrícia
Subjects:
Endometriosis
Dysmenorrhea
Dyspareunia
Alelles
Polymorphism, genetic
Genotype
Receptors, leptin
Inflammatory cytokines
Pelvic pain
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032025000100229&lng=en&tlng=en
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