Association of genotypes of cows of the Kholmogory breed by beta-casein with milk productivity

The aim of the study is to identify the frequency of occurrence of various allelic variants and genotypes of beta-casein in cows of the Kholmogory breed and their relationship with dairy productivity. The tasks of the research are genotyping of cattle of the Kholmogory breed by the beta-casein locus...

Full description

Saved in:
Bibliographic Details
Main Authors: E. V. Parygina, N. A. Khudyakova, O. V. Tulinova, A. A. Pervukhina, I. V. Selkova, I. S. Kozhevnikova, M. A. Kudrina
Format: Article
Language:Russian
Published: Federal Agricultural Research Center of the North-East named N.V. Rudnitsky 2022-12-01
Series:Аграрная наука Евро-Северо-Востока
Subjects:
Online Access:https://www.agronauka-sv.ru/jour/article/view/1184
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849249577433038848
author E. V. Parygina
N. A. Khudyakova
O. V. Tulinova
A. A. Pervukhina
I. V. Selkova
I. S. Kozhevnikova
M. A. Kudrina
author_facet E. V. Parygina
N. A. Khudyakova
O. V. Tulinova
A. A. Pervukhina
I. V. Selkova
I. S. Kozhevnikova
M. A. Kudrina
author_sort E. V. Parygina
collection DOAJ
description The aim of the study is to identify the frequency of occurrence of various allelic variants and genotypes of beta-casein in cows of the Kholmogory breed and their relationship with dairy productivity. The tasks of the research are genotyping of cattle of the Kholmogory breed by the beta-casein locus and establishing its connection with qualitative and quantitative indicators of dairy productivity. As the objects for the research there were taken 150 cows of the 1st, 2nd and 3rd lactation. An allele-specific variant of the PCR method (AS-PCR) was used to identify A1 and A2 beta-casein. As the result it had been established that in the studied part of the herd, 23 % of animals had the A2A2 genotype, 43 % of animals had the A1A1 genotype and 34 % of animals had the A1A2 genotype. For 100 days of the first lactation, animals with A1A2 genotype showed the highest value in milk yield. Animals with A2A2 genotype for 305 days of lactation had the highest milk yield and the amount of milk protein, however, the difference was not statistically significant compared to the animals with A1A2 genotype. Genotype A1A1 has lower indicators by all the parameters studied, with a significant difference relative to genotypes A1A2 and A2A2. Thus, the study of CSN2 is a promising area of scientific research, and the results of the study of beta-casein genotypes can be used as a marker selection in improving the herds of the Kholmogory breed.
format Article
id doaj-art-e994f4e2a14f41b49781adcb4f9ce5b9
institution Kabale University
issn 2072-9081
2500-1396
language Russian
publishDate 2022-12-01
publisher Federal Agricultural Research Center of the North-East named N.V. Rudnitsky
record_format Article
series Аграрная наука Евро-Северо-Востока
spelling doaj-art-e994f4e2a14f41b49781adcb4f9ce5b92025-08-20T03:57:31ZrusFederal Agricultural Research Center of the North-East named N.V. RudnitskyАграрная наука Евро-Северо-Востока2072-90812500-13962022-12-0123687788310.30766/2072-9081.2022.23.6.877-883623Association of genotypes of cows of the Kholmogory breed by beta-casein with milk productivityE. V. Parygina0N. A. Khudyakova1O. V. Tulinova2A. A. Pervukhina3I. V. Selkova4I. S. Kozhevnikova5M. A. Kudrina6Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of SciencesLaverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of SciencesRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L.K. Ernst Federal Research Center for Animal HusbandryLaverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of SciencesLaverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of SciencesLaverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of SciencesLaverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of SciencesThe aim of the study is to identify the frequency of occurrence of various allelic variants and genotypes of beta-casein in cows of the Kholmogory breed and their relationship with dairy productivity. The tasks of the research are genotyping of cattle of the Kholmogory breed by the beta-casein locus and establishing its connection with qualitative and quantitative indicators of dairy productivity. As the objects for the research there were taken 150 cows of the 1st, 2nd and 3rd lactation. An allele-specific variant of the PCR method (AS-PCR) was used to identify A1 and A2 beta-casein. As the result it had been established that in the studied part of the herd, 23 % of animals had the A2A2 genotype, 43 % of animals had the A1A1 genotype and 34 % of animals had the A1A2 genotype. For 100 days of the first lactation, animals with A1A2 genotype showed the highest value in milk yield. Animals with A2A2 genotype for 305 days of lactation had the highest milk yield and the amount of milk protein, however, the difference was not statistically significant compared to the animals with A1A2 genotype. Genotype A1A1 has lower indicators by all the parameters studied, with a significant difference relative to genotypes A1A2 and A2A2. Thus, the study of CSN2 is a promising area of scientific research, and the results of the study of beta-casein genotypes can be used as a marker selection in improving the herds of the Kholmogory breed.https://www.agronauka-sv.ru/jour/article/view/1184milk proteingenotypefrequency of occurrencecowarkhangelsk region
spellingShingle E. V. Parygina
N. A. Khudyakova
O. V. Tulinova
A. A. Pervukhina
I. V. Selkova
I. S. Kozhevnikova
M. A. Kudrina
Association of genotypes of cows of the Kholmogory breed by beta-casein with milk productivity
Аграрная наука Евро-Северо-Востока
milk protein
genotype
frequency of occurrence
cow
arkhangelsk region
title Association of genotypes of cows of the Kholmogory breed by beta-casein with milk productivity
title_full Association of genotypes of cows of the Kholmogory breed by beta-casein with milk productivity
title_fullStr Association of genotypes of cows of the Kholmogory breed by beta-casein with milk productivity
title_full_unstemmed Association of genotypes of cows of the Kholmogory breed by beta-casein with milk productivity
title_short Association of genotypes of cows of the Kholmogory breed by beta-casein with milk productivity
title_sort association of genotypes of cows of the kholmogory breed by beta casein with milk productivity
topic milk protein
genotype
frequency of occurrence
cow
arkhangelsk region
url https://www.agronauka-sv.ru/jour/article/view/1184
work_keys_str_mv AT evparygina associationofgenotypesofcowsofthekholmogorybreedbybetacaseinwithmilkproductivity
AT nakhudyakova associationofgenotypesofcowsofthekholmogorybreedbybetacaseinwithmilkproductivity
AT ovtulinova associationofgenotypesofcowsofthekholmogorybreedbybetacaseinwithmilkproductivity
AT aapervukhina associationofgenotypesofcowsofthekholmogorybreedbybetacaseinwithmilkproductivity
AT ivselkova associationofgenotypesofcowsofthekholmogorybreedbybetacaseinwithmilkproductivity
AT iskozhevnikova associationofgenotypesofcowsofthekholmogorybreedbybetacaseinwithmilkproductivity
AT makudrina associationofgenotypesofcowsofthekholmogorybreedbybetacaseinwithmilkproductivity