Modern methods and materials used to treat root perforation: effectiveness comparison

Abstract This study aims to experimentally compare the efficacy of different endodontic materials (iRoot BP Plus, Biodentine, MTA, Rootdent, and Trioxide) in the treatment of pulpitis and perforations on extracted tooth specimens. Additionally, the study aims to investigate the influence of iRoot BP...

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Main Authors: XiaoLan Ma, Hua Xu, Xuefang Chen, Qian Zou, Junrong Wang, Yunmeng Da, Huisu Yin
Format: Article
Language:English
Published: Springer 2024-01-01
Series:Journal of Materials Science: Materials in Medicine
Online Access:https://doi.org/10.1007/s10856-023-06770-y
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author XiaoLan Ma
Hua Xu
Xuefang Chen
Qian Zou
Junrong Wang
Yunmeng Da
Huisu Yin
author_facet XiaoLan Ma
Hua Xu
Xuefang Chen
Qian Zou
Junrong Wang
Yunmeng Da
Huisu Yin
author_sort XiaoLan Ma
collection DOAJ
description Abstract This study aims to experimentally compare the efficacy of different endodontic materials (iRoot BP Plus, Biodentine, MTA, Rootdent, and Trioxide) in the treatment of pulpitis and perforations on extracted tooth specimens. Additionally, the study aims to investigate the influence of iRoot BP Plus endodontic material on the regenerative processes following pulp amputation in laboratory animals. The secondary goal is to evaluate the effect of iRoot BP Plus on the restoration process in laboratory animals after pulp removal. The study presents a micropermeability analysis of the selected biomaterials performed on a sample of 50 single-rooted apical teeth in 2022. All teeth underwent endodontic treatment. Changes in molar morphology were investigated with eight laboratory animals (rabbits, 3 months old, all males) after simulated pulp removal and subsequent treatment with the iRoot BP Plus biomaterials. iRoot BP Plus appeared to be more effective in retrograde apical root filling than other biomaterials, as evidenced by its higher sealing effect. An experiment involving animal participants revealed the presence of protective adaptive mechanisms, which manifested in the form of an inflammatory process within 6 weeks after the dental pulp was removed. The connective tissue replaced the necrosis, and new capillaries began to form intensively. These dental outcomes suggest that iRoot BP Plus enables hermetical sealing in tooth restoration with good adhesion. Thus, it may have the ability to promote more active tissue regeneration after pulp removal. Graphical Abstract
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spelling doaj-art-e99355f6149045e893db86b5ffa132192025-08-20T01:57:15ZengSpringerJournal of Materials Science: Materials in Medicine1573-48382024-01-0135111110.1007/s10856-023-06770-yModern methods and materials used to treat root perforation: effectiveness comparisonXiaoLan Ma0Hua Xu1Xuefang Chen2Qian Zou3Junrong Wang4Yunmeng Da5Huisu Yin6Department of Oral Medicine, Hebei Eye HospitalDepartment of Oral Medicine, Hebei Eye HospitalDepartment of Oral Medicine, Hebei Eye HospitalDepartment of Oral Medicine, Hebei Eye HospitalDepartment of Oral and Maxillofacial Surgery, Hebei Eye HospitalDepartment of Prosthodontics, Hebei Eye HospitalDepartment of Science and Education, Hebei Eye HospitalAbstract This study aims to experimentally compare the efficacy of different endodontic materials (iRoot BP Plus, Biodentine, MTA, Rootdent, and Trioxide) in the treatment of pulpitis and perforations on extracted tooth specimens. Additionally, the study aims to investigate the influence of iRoot BP Plus endodontic material on the regenerative processes following pulp amputation in laboratory animals. The secondary goal is to evaluate the effect of iRoot BP Plus on the restoration process in laboratory animals after pulp removal. The study presents a micropermeability analysis of the selected biomaterials performed on a sample of 50 single-rooted apical teeth in 2022. All teeth underwent endodontic treatment. Changes in molar morphology were investigated with eight laboratory animals (rabbits, 3 months old, all males) after simulated pulp removal and subsequent treatment with the iRoot BP Plus biomaterials. iRoot BP Plus appeared to be more effective in retrograde apical root filling than other biomaterials, as evidenced by its higher sealing effect. An experiment involving animal participants revealed the presence of protective adaptive mechanisms, which manifested in the form of an inflammatory process within 6 weeks after the dental pulp was removed. The connective tissue replaced the necrosis, and new capillaries began to form intensively. These dental outcomes suggest that iRoot BP Plus enables hermetical sealing in tooth restoration with good adhesion. Thus, it may have the ability to promote more active tissue regeneration after pulp removal. Graphical Abstracthttps://doi.org/10.1007/s10856-023-06770-y
spellingShingle XiaoLan Ma
Hua Xu
Xuefang Chen
Qian Zou
Junrong Wang
Yunmeng Da
Huisu Yin
Modern methods and materials used to treat root perforation: effectiveness comparison
Journal of Materials Science: Materials in Medicine
title Modern methods and materials used to treat root perforation: effectiveness comparison
title_full Modern methods and materials used to treat root perforation: effectiveness comparison
title_fullStr Modern methods and materials used to treat root perforation: effectiveness comparison
title_full_unstemmed Modern methods and materials used to treat root perforation: effectiveness comparison
title_short Modern methods and materials used to treat root perforation: effectiveness comparison
title_sort modern methods and materials used to treat root perforation effectiveness comparison
url https://doi.org/10.1007/s10856-023-06770-y
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AT xuefangchen modernmethodsandmaterialsusedtotreatrootperforationeffectivenesscomparison
AT qianzou modernmethodsandmaterialsusedtotreatrootperforationeffectivenesscomparison
AT junrongwang modernmethodsandmaterialsusedtotreatrootperforationeffectivenesscomparison
AT yunmengda modernmethodsandmaterialsusedtotreatrootperforationeffectivenesscomparison
AT huisuyin modernmethodsandmaterialsusedtotreatrootperforationeffectivenesscomparison