Effect of autologous platelet-rich plasma treatment on patients with thin endometrium
Introduction: The success of frozen embryo transfer cycles depends on a delicate interaction between embryo quality and endometrium. Low pregnancy rates are associated with a thin endometrium. Objective: To evaluate the effect of autologous platelet-rich plasma treatment on patients with thin endome...
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| Format: | Article |
| Language: | Spanish |
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Editorial Ciencias Médicas - ECIMED
2022-06-01
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| Series: | Revista Cubana de Medicina Militar |
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| Online Access: | http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1802 |
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| author | Tung Nguyen Thanh Ai Hoang Van Son Trinh The Lan Do Ngoc Hang Doan Thi Trang Quan Van Khoa Ba Tran Sang Trieu Tien |
| author_facet | Tung Nguyen Thanh Ai Hoang Van Son Trinh The Lan Do Ngoc Hang Doan Thi Trang Quan Van Khoa Ba Tran Sang Trieu Tien |
| author_sort | Tung Nguyen Thanh |
| collection | DOAJ |
| description | Introduction: The success of frozen embryo transfer cycles depends on a delicate interaction between embryo quality and endometrium. Low pregnancy rates are associated with a thin endometrium.
Objective: To evaluate the effect of autologous platelet-rich plasma treatment on patients with thin endometrium.
Methods: In 34 patients with thin endometrium (< 7 mm), canceled in the previous frozen embryo transfer cycles, autologous platelet-rich plasma was prepared, from autologous peripheral vein blood; intrauterine infusion was given during hormone replacement therapy in frozen embryo transfer cycles. Frozen embryo transfer was performed when the endometrium thickness reached ≥ 7mm.
Results: Six patients canceled the embryo transfer cycle due to endometrium thickness did not reach 7 mm; 28 patients got endometrial thickness ≥ 7 mm and performed frozen embryo transfer. The endometrial thickness was 7.5 ± 0.8 mm, which was significantly thicker than in the previous cycles (5.6 ± 0.79 mm) with p< 0.002, the implantation rate was 23.07 %, and the clinical pregnancy rate was 12/28 (42.8 %).
Conclusion: Autologous platelet-rich plasma improves the endometrial thickness and the pregnancy rate outcomes in women with thin endometrium. |
| format | Article |
| id | doaj-art-e991eb9c081e4bdbbdaac0ee69dffe01 |
| institution | OA Journals |
| issn | 1561-3046 |
| language | Spanish |
| publishDate | 2022-06-01 |
| publisher | Editorial Ciencias Médicas - ECIMED |
| record_format | Article |
| series | Revista Cubana de Medicina Militar |
| spelling | doaj-art-e991eb9c081e4bdbbdaac0ee69dffe012025-08-20T01:55:45ZspaEditorial Ciencias Médicas - ECIMEDRevista Cubana de Medicina Militar1561-30462022-06-01512e02201802e02201802579Effect of autologous platelet-rich plasma treatment on patients with thin endometriumTung Nguyen Thanh0Ai Hoang Van1Son Trinh The2Lan Do Ngoc3Hang Doan Thi4Trang Quan Van5Khoa Ba Tran6Sang Trieu Tien7Military Institute of Clinical Embryology and Histology, Millitary Medical University, Hanoi, VietnamMilitary Institute of Clinical Embryology and Histology, Millitary Medical University, Hanoi, VietnamMilitary Institute of Clinical Embryology and Histology, Millitary Medical University, Hanoi, VietnamMilitary Institute of Clinical Embryology and Histology, Millitary Medical University, Hanoi, VietnamMilitary Institute of Clinical Embryology and Histology, Millitary Medical University, Hanoi, VietnamMilitary Institute of Clinical Embryology and Histology, Millitary Medical University, Hanoi, Vietnam108 Millitary Central Hospital, Hanoi, VietnamDept. Biology and Medical Genetic, Vietnam Military Medical University, Hanoi, 121-08, VietnamIntroduction: The success of frozen embryo transfer cycles depends on a delicate interaction between embryo quality and endometrium. Low pregnancy rates are associated with a thin endometrium. Objective: To evaluate the effect of autologous platelet-rich plasma treatment on patients with thin endometrium. Methods: In 34 patients with thin endometrium (< 7 mm), canceled in the previous frozen embryo transfer cycles, autologous platelet-rich plasma was prepared, from autologous peripheral vein blood; intrauterine infusion was given during hormone replacement therapy in frozen embryo transfer cycles. Frozen embryo transfer was performed when the endometrium thickness reached ≥ 7mm. Results: Six patients canceled the embryo transfer cycle due to endometrium thickness did not reach 7 mm; 28 patients got endometrial thickness ≥ 7 mm and performed frozen embryo transfer. The endometrial thickness was 7.5 ± 0.8 mm, which was significantly thicker than in the previous cycles (5.6 ± 0.79 mm) with p< 0.002, the implantation rate was 23.07 %, and the clinical pregnancy rate was 12/28 (42.8 %). Conclusion: Autologous platelet-rich plasma improves the endometrial thickness and the pregnancy rate outcomes in women with thin endometrium.http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1802frozen embryo transferplatelet-rich plasmathin endometriumendometrium thickness. |
| spellingShingle | Tung Nguyen Thanh Ai Hoang Van Son Trinh The Lan Do Ngoc Hang Doan Thi Trang Quan Van Khoa Ba Tran Sang Trieu Tien Effect of autologous platelet-rich plasma treatment on patients with thin endometrium Revista Cubana de Medicina Militar frozen embryo transfer platelet-rich plasma thin endometrium endometrium thickness. |
| title | Effect of autologous platelet-rich plasma treatment on patients with thin endometrium |
| title_full | Effect of autologous platelet-rich plasma treatment on patients with thin endometrium |
| title_fullStr | Effect of autologous platelet-rich plasma treatment on patients with thin endometrium |
| title_full_unstemmed | Effect of autologous platelet-rich plasma treatment on patients with thin endometrium |
| title_short | Effect of autologous platelet-rich plasma treatment on patients with thin endometrium |
| title_sort | effect of autologous platelet rich plasma treatment on patients with thin endometrium |
| topic | frozen embryo transfer platelet-rich plasma thin endometrium endometrium thickness. |
| url | http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1802 |
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