Thyroid metastasis from nasopharyngeal cancer: a case report

Background. Nasopharyngeal cancer is a rare head and neck cancer with a relatively high risk of locoregional recurrence and distant metastases. The most common sites of metastases are bones (70–80 %) followed by liver (30 %), lung (18 %), and lymph node (axillary, mediastinal, pelvic, and inguinal)....

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Main Authors: D. M. Fatkullin, A. O. Guz, A. V. Garev, A. S. Zakharov, M. I. Sokolova, I. G. Shesler, K. S. Aristarkhova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2023-09-01
Series:Сибирский онкологический журнал
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Online Access:https://www.siboncoj.ru/jour/article/view/2691
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author D. M. Fatkullin
A. O. Guz
A. V. Garev
A. S. Zakharov
M. I. Sokolova
I. G. Shesler
K. S. Aristarkhova
author_facet D. M. Fatkullin
A. O. Guz
A. V. Garev
A. S. Zakharov
M. I. Sokolova
I. G. Shesler
K. S. Aristarkhova
author_sort D. M. Fatkullin
collection DOAJ
description Background. Nasopharyngeal cancer is a rare head and neck cancer with a relatively high risk of locoregional recurrence and distant metastases. The most common sites of metastases are bones (70–80 %) followed by liver (30 %), lung (18 %), and lymph node (axillary, mediastinal, pelvic, and inguinal). Thyroid gland is an uncommon site of metastasis with an incidence ranging from 0.5% to 24 %. Thyroid metastasis from nasopharyngeal cancer has been reported in only 9 cases in the world literature and no one in Russia. Case report. We report a case of thyroid metastasis from nasopharyngeal cancer found incidentally in a 53-year-old female patient. Conclusion. Metastases to the thyroid gland are rare, and patients with metastatic thyroid disease rarely present with organ-specifc symptoms, thus raising diagnostic diffculties for both clinicians and the pathologists. This clinical report demonstrates the diffculties of differential diagnosis,as well as the importance of a thorough collection of complaints, anamnesis, and clinical examination.
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institution Kabale University
issn 1814-4861
2312-3168
language Russian
publishDate 2023-09-01
publisher Russian Academy of Sciences, Tomsk National Research Medical Center
record_format Article
series Сибирский онкологический журнал
spelling doaj-art-e98f5fee6a584ff8b17ec72bd934c5592025-08-20T03:43:40ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682023-09-0122414915310.21294/1814-4861-2023-22-4-149-1531153Thyroid metastasis from nasopharyngeal cancer: a case reportD. M. Fatkullin0A. O. Guz1A. V. Garev2A. S. Zakharov3M. I. Sokolova4I. G. Shesler5K. S. Aristarkhova6Chelyabinsk Regional Clinical Center of Oncology and Nuclear MedicineChelyabinsk Regional Clinical Center of Oncology and Nuclear MedicineChelyabinsk Regional Clinical Center of Oncology and Nuclear MedicineChelyabinsk Regional Clinical Center of Oncology and Nuclear MedicineChelyabinsk Regional Clinical Center of Oncology and Nuclear MedicineChelyabinsk Regional Clinical Center of Oncology and Nuclear MedicineChelyabinsk Regional Clinical Center of Oncology and Nuclear MedicineBackground. Nasopharyngeal cancer is a rare head and neck cancer with a relatively high risk of locoregional recurrence and distant metastases. The most common sites of metastases are bones (70–80 %) followed by liver (30 %), lung (18 %), and lymph node (axillary, mediastinal, pelvic, and inguinal). Thyroid gland is an uncommon site of metastasis with an incidence ranging from 0.5% to 24 %. Thyroid metastasis from nasopharyngeal cancer has been reported in only 9 cases in the world literature and no one in Russia. Case report. We report a case of thyroid metastasis from nasopharyngeal cancer found incidentally in a 53-year-old female patient. Conclusion. Metastases to the thyroid gland are rare, and patients with metastatic thyroid disease rarely present with organ-specifc symptoms, thus raising diagnostic diffculties for both clinicians and the pathologists. This clinical report demonstrates the diffculties of differential diagnosis,as well as the importance of a thorough collection of complaints, anamnesis, and clinical examination.https://www.siboncoj.ru/jour/article/view/2691nasopharyngeal carcinomathyroid glandthyroid metastasis
spellingShingle D. M. Fatkullin
A. O. Guz
A. V. Garev
A. S. Zakharov
M. I. Sokolova
I. G. Shesler
K. S. Aristarkhova
Thyroid metastasis from nasopharyngeal cancer: a case report
Сибирский онкологический журнал
nasopharyngeal carcinoma
thyroid gland
thyroid metastasis
title Thyroid metastasis from nasopharyngeal cancer: a case report
title_full Thyroid metastasis from nasopharyngeal cancer: a case report
title_fullStr Thyroid metastasis from nasopharyngeal cancer: a case report
title_full_unstemmed Thyroid metastasis from nasopharyngeal cancer: a case report
title_short Thyroid metastasis from nasopharyngeal cancer: a case report
title_sort thyroid metastasis from nasopharyngeal cancer a case report
topic nasopharyngeal carcinoma
thyroid gland
thyroid metastasis
url https://www.siboncoj.ru/jour/article/view/2691
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AT avgarev thyroidmetastasisfromnasopharyngealcanceracasereport
AT aszakharov thyroidmetastasisfromnasopharyngealcanceracasereport
AT misokolova thyroidmetastasisfromnasopharyngealcanceracasereport
AT igshesler thyroidmetastasisfromnasopharyngealcanceracasereport
AT ksaristarkhova thyroidmetastasisfromnasopharyngealcanceracasereport