Synthesis of Cr3+-doped Al2O3 in nanoscale for bio-labels in myocardial cells
The Al2O3: Cr3+ light-converting materials were successfully synthesized via co-precipitation, resulting in a grain size ranging from 100 to 400 nm. Under excitation wavelengths spanning from 360 to 650 nm, a distinct near-infrared (NIR) emission at 695 nm was observed. Through optimization, it has...
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Elsevier
2025-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025000817 |
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| author | Sida Chen Jian Hou Yang Huang Jinyu Pan Kaizheng Liu Guangxian Chen Zhongkai Wu Haoyi Wu |
| author_facet | Sida Chen Jian Hou Yang Huang Jinyu Pan Kaizheng Liu Guangxian Chen Zhongkai Wu Haoyi Wu |
| author_sort | Sida Chen |
| collection | DOAJ |
| description | The Al2O3: Cr3+ light-converting materials were successfully synthesized via co-precipitation, resulting in a grain size ranging from 100 to 400 nm. Under excitation wavelengths spanning from 360 to 650 nm, a distinct near-infrared (NIR) emission at 695 nm was observed. Through optimization, it has been established that a Cr3+ doping concentration of 1.0 mol% results from the optimal emission intensity. The material shows relatively stable in water and it was employed to cultivate the H9C2 cells, and the NIR emission from the cells was observed, indicating the successful absorption of the material by the cells. Additionally, the toxicity of the material was examined, by reducing the concentration to 2 nM/mL, the toxicity of the material was significantly reduced to a promising level. Therefore, the suitable grain size, NIR emission and the biocompatibility renders this material a candidate in cell imaging. |
| format | Article |
| id | doaj-art-e98e363754cd41d88ba78d78232cfb70 |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-e98e363754cd41d88ba78d78232cfb702025-01-17T04:51:56ZengElsevierHeliyon2405-84402025-01-01111e41701Synthesis of Cr3+-doped Al2O3 in nanoscale for bio-labels in myocardial cellsSida Chen0Jian Hou1Yang Huang2Jinyu Pan3Kaizheng Liu4Guangxian Chen5Zhongkai Wu6Haoyi Wu7Department of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, GD, ChinaDepartment of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, GD, ChinaDepartment of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, GD, ChinaDepartment of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, GD, ChinaDepartment of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, GD, ChinaDepartment of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, GD, China; Corresponding author.gx.chan@163.comDepartment of Cardiac Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, GD, China; Corresponding author.School of Physics and Optoelectronic Engineering, Guangdong University of Technology, HEMC, Guangzhou, China; Corresponding author.The Al2O3: Cr3+ light-converting materials were successfully synthesized via co-precipitation, resulting in a grain size ranging from 100 to 400 nm. Under excitation wavelengths spanning from 360 to 650 nm, a distinct near-infrared (NIR) emission at 695 nm was observed. Through optimization, it has been established that a Cr3+ doping concentration of 1.0 mol% results from the optimal emission intensity. The material shows relatively stable in water and it was employed to cultivate the H9C2 cells, and the NIR emission from the cells was observed, indicating the successful absorption of the material by the cells. Additionally, the toxicity of the material was examined, by reducing the concentration to 2 nM/mL, the toxicity of the material was significantly reduced to a promising level. Therefore, the suitable grain size, NIR emission and the biocompatibility renders this material a candidate in cell imaging.http://www.sciencedirect.com/science/article/pii/S2405844025000817Al2O3: Cr3+Near-infrared emissionCell imaging |
| spellingShingle | Sida Chen Jian Hou Yang Huang Jinyu Pan Kaizheng Liu Guangxian Chen Zhongkai Wu Haoyi Wu Synthesis of Cr3+-doped Al2O3 in nanoscale for bio-labels in myocardial cells Heliyon Al2O3: Cr3+ Near-infrared emission Cell imaging |
| title | Synthesis of Cr3+-doped Al2O3 in nanoscale for bio-labels in myocardial cells |
| title_full | Synthesis of Cr3+-doped Al2O3 in nanoscale for bio-labels in myocardial cells |
| title_fullStr | Synthesis of Cr3+-doped Al2O3 in nanoscale for bio-labels in myocardial cells |
| title_full_unstemmed | Synthesis of Cr3+-doped Al2O3 in nanoscale for bio-labels in myocardial cells |
| title_short | Synthesis of Cr3+-doped Al2O3 in nanoscale for bio-labels in myocardial cells |
| title_sort | synthesis of cr3 doped al2o3 in nanoscale for bio labels in myocardial cells |
| topic | Al2O3: Cr3+ Near-infrared emission Cell imaging |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025000817 |
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