Safety and Clinical Efficacy of Prostatic Artery Embolization in Patients with Indwelling Urinary Catheter for Benign Hyperplasia—A Multicenter Study
<b>Background/Objectives</b>: This multicentric study aimed to evaluate the efficacy and safety of prostatic artery embolization (PAE) to remove indwelling urinary catheter (IUC) in patients with symptomatic benign prostatic hyperplasia (BPH). Secondary objectives were to identify featur...
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2024-12-01
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| Online Access: | https://www.mdpi.com/2075-4418/14/24/2864 |
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| author | Jules Pouchot Amandine Crombé Luc Burlet Fadi Farah Pierre Baseilhac Arthur David François Petitpierre Rim Maaloum Yann Le Bras Gaele Pagnoux Haytham Derbel Hicham Kobeiter Matthias Barral Julien Frandon Clément Marcelin Clément Klein Eva Jambon |
| author_facet | Jules Pouchot Amandine Crombé Luc Burlet Fadi Farah Pierre Baseilhac Arthur David François Petitpierre Rim Maaloum Yann Le Bras Gaele Pagnoux Haytham Derbel Hicham Kobeiter Matthias Barral Julien Frandon Clément Marcelin Clément Klein Eva Jambon |
| author_sort | Jules Pouchot |
| collection | DOAJ |
| description | <b>Background/Objectives</b>: This multicentric study aimed to evaluate the efficacy and safety of prostatic artery embolization (PAE) to remove indwelling urinary catheter (IUC) in patients with symptomatic benign prostatic hyperplasia (BPH). Secondary objectives were to identify features associated with post-PAE catheter-free survival (PCFS). <b>Methods</b>: All consecutive patients who underwent PAE for IUC related to BPH with a follow-up of at least 2 years (except for early death) in 6 French University Hospitals were retrospectively included. Clinical efficacy was defined as the removal of the IUC after PAE (through a trial without catheter [TWOC]) and evaluated at regular intervals. Chi-square tests, Wilcoxon tests and multivariable binary logistic regressions were utilized to investigate predictors of TWOC success. Univariable and multivariable Cox regressions were utilized to investigate predictors of PCFS in patients with TWOC success. <b>Results</b>: 140 men with IUC (median age: 82.5 years, interquartile range [IQR] = 73–88.2 years, range: 46–100) who underwent PAE between January 2017 and March 2021 were included. Initial successful catheter removal (TWOC success) following PAE occurred in 113/140 (80.7%) patients, and 3/140 (2.1%) patients encountered major complications. In patients with TWOC success, PCFS at 6 months, 1 year and 2 years were 87.5% (95%CI: 81.4–94.1), 84.4% (95%CI: 77.7–91.7) and 79% (71.3–87.4), respectively. No independent predictive factors for TWOC success and PCFS were identified. <b>Conclusions</b>: PAE should be considered as a safe option with good clinical efficacy in the short and long term for elderly and inoperable patients with IUC due to symptomatic BPH. |
| format | Article |
| id | doaj-art-e98c9d5bf29d403cbf5b2e889c75ad10 |
| institution | DOAJ |
| issn | 2075-4418 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
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| series | Diagnostics |
| spelling | doaj-art-e98c9d5bf29d403cbf5b2e889c75ad102025-08-20T02:55:52ZengMDPI AGDiagnostics2075-44182024-12-011424286410.3390/diagnostics14242864Safety and Clinical Efficacy of Prostatic Artery Embolization in Patients with Indwelling Urinary Catheter for Benign Hyperplasia—A Multicenter StudyJules Pouchot0Amandine Crombé1Luc Burlet2Fadi Farah3Pierre Baseilhac4Arthur David5François Petitpierre6Rim Maaloum7Yann Le Bras8Gaele Pagnoux9Haytham Derbel10Hicham Kobeiter11Matthias Barral12Julien Frandon13Clément Marcelin14Clément Klein15Eva Jambon16Service de Radiologie et Imagerie Médicale de L’adulte, Centre Hospitalier Universitaire de Bordeaux, Place Amélie Raba Léon, 33076 Bordeaux, FranceService de Radiologie et Imagerie Médicale de L’adulte, Centre Hospitalier Universitaire de Bordeaux, Place Amélie Raba Léon, 33076 Bordeaux, FranceDepartment of Medical Imaging, IPI Plateform, Nîmes University Hospital, University of Montpellier, Medical Imaging Group Nîmes, IMAGINE, 30029 Nîmes, FranceDepartment of Diagnostic and Interventional Medical Imaging, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Henri Mondor, Université Paris Est, 94000 Créteil, FranceDepartment of Uroradiology, Hospices Civils de Lyon, Hôpital Edouard Herriot, 69003 Lyon, FranceDepartment of Radiology, Nantes University Hospital, University of Medicine, 44000 Nantes, FranceService de Radiologie et Imagerie Médicale de L’adulte, Centre Hospitalier Universitaire de Bordeaux, Place Amélie Raba Léon, 33076 Bordeaux, FranceService de Radiologie et Imagerie Médicale de L’adulte, Centre Hospitalier Universitaire de Bordeaux, Place Amélie Raba Léon, 33076 Bordeaux, FranceService de Radiologie et Imagerie Médicale de L’adulte, Centre Hospitalier Universitaire de Bordeaux, Place Amélie Raba Léon, 33076 Bordeaux, FranceDepartment of Uroradiology, Hospices Civils de Lyon, Hôpital Edouard Herriot, 69003 Lyon, FranceDepartment of Diagnostic and Interventional Medical Imaging, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Henri Mondor, Université Paris Est, 94000 Créteil, FranceDepartment of Diagnostic and Interventional Medical Imaging, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Henri Mondor, Université Paris Est, 94000 Créteil, FranceService de Radiologie, Assistance Publique-Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 75970 Paris, FranceDepartment of Medical Imaging, IPI Plateform, Nîmes University Hospital, University of Montpellier, Medical Imaging Group Nîmes, IMAGINE, 30029 Nîmes, FranceService de Radiologie et Imagerie Médicale de L’adulte, Centre Hospitalier Universitaire de Bordeaux, Place Amélie Raba Léon, 33076 Bordeaux, FranceService de Chirurgie Urologique, Centre Hospitalier Universitaire de Bordeaux, Place Amélie Raba Léon, 33076 Bordeaux, FranceService de Radiologie et Imagerie Médicale de L’adulte, Centre Hospitalier Universitaire de Bordeaux, Place Amélie Raba Léon, 33076 Bordeaux, France<b>Background/Objectives</b>: This multicentric study aimed to evaluate the efficacy and safety of prostatic artery embolization (PAE) to remove indwelling urinary catheter (IUC) in patients with symptomatic benign prostatic hyperplasia (BPH). Secondary objectives were to identify features associated with post-PAE catheter-free survival (PCFS). <b>Methods</b>: All consecutive patients who underwent PAE for IUC related to BPH with a follow-up of at least 2 years (except for early death) in 6 French University Hospitals were retrospectively included. Clinical efficacy was defined as the removal of the IUC after PAE (through a trial without catheter [TWOC]) and evaluated at regular intervals. Chi-square tests, Wilcoxon tests and multivariable binary logistic regressions were utilized to investigate predictors of TWOC success. Univariable and multivariable Cox regressions were utilized to investigate predictors of PCFS in patients with TWOC success. <b>Results</b>: 140 men with IUC (median age: 82.5 years, interquartile range [IQR] = 73–88.2 years, range: 46–100) who underwent PAE between January 2017 and March 2021 were included. Initial successful catheter removal (TWOC success) following PAE occurred in 113/140 (80.7%) patients, and 3/140 (2.1%) patients encountered major complications. In patients with TWOC success, PCFS at 6 months, 1 year and 2 years were 87.5% (95%CI: 81.4–94.1), 84.4% (95%CI: 77.7–91.7) and 79% (71.3–87.4), respectively. No independent predictive factors for TWOC success and PCFS were identified. <b>Conclusions</b>: PAE should be considered as a safe option with good clinical efficacy in the short and long term for elderly and inoperable patients with IUC due to symptomatic BPH.https://www.mdpi.com/2075-4418/14/24/2864prostate artery embolizationprostate benign hyperplasiaurinary cathetersafetytreatment outcome |
| spellingShingle | Jules Pouchot Amandine Crombé Luc Burlet Fadi Farah Pierre Baseilhac Arthur David François Petitpierre Rim Maaloum Yann Le Bras Gaele Pagnoux Haytham Derbel Hicham Kobeiter Matthias Barral Julien Frandon Clément Marcelin Clément Klein Eva Jambon Safety and Clinical Efficacy of Prostatic Artery Embolization in Patients with Indwelling Urinary Catheter for Benign Hyperplasia—A Multicenter Study Diagnostics prostate artery embolization prostate benign hyperplasia urinary catheter safety treatment outcome |
| title | Safety and Clinical Efficacy of Prostatic Artery Embolization in Patients with Indwelling Urinary Catheter for Benign Hyperplasia—A Multicenter Study |
| title_full | Safety and Clinical Efficacy of Prostatic Artery Embolization in Patients with Indwelling Urinary Catheter for Benign Hyperplasia—A Multicenter Study |
| title_fullStr | Safety and Clinical Efficacy of Prostatic Artery Embolization in Patients with Indwelling Urinary Catheter for Benign Hyperplasia—A Multicenter Study |
| title_full_unstemmed | Safety and Clinical Efficacy of Prostatic Artery Embolization in Patients with Indwelling Urinary Catheter for Benign Hyperplasia—A Multicenter Study |
| title_short | Safety and Clinical Efficacy of Prostatic Artery Embolization in Patients with Indwelling Urinary Catheter for Benign Hyperplasia—A Multicenter Study |
| title_sort | safety and clinical efficacy of prostatic artery embolization in patients with indwelling urinary catheter for benign hyperplasia a multicenter study |
| topic | prostate artery embolization prostate benign hyperplasia urinary catheter safety treatment outcome |
| url | https://www.mdpi.com/2075-4418/14/24/2864 |
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