New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptor
Migraine is a long-lasting neurological disorder with significant negative impact not only on the patient’s life, but also on society. For many years, preventive treatment of migraine included drugs developed for diseases other than migraine such as hypertension, depression, and epilepsy. During th...
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| Format: | Article |
| Language: | English |
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Vilnius University Press
2019-12-01
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| Series: | Neurologijos seminarai |
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| Online Access: | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27765 |
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| _version_ | 1832593095440465920 |
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| author | K. Ryliškienė D. Jatužis A. Vaitkus |
| author_facet | K. Ryliškienė D. Jatužis A. Vaitkus |
| author_sort | K. Ryliškienė |
| collection | DOAJ |
| description |
Migraine is a long-lasting neurological disorder with significant negative impact not only on the patient’s life, but also on society. For many years, preventive treatment of migraine included drugs developed for diseases other than migraine such as hypertension, depression, and epilepsy. During the last decade, blocking calcitonin gene-related peptide (CGRP) has emerged as a possible mechanism for preventing migraine attacks, and monoclonal antibodies against CGRP and its receptor for the specific migraine prophylaxis have been developed. Results of clinical trials, safety and tolerability of the new class of drugs as well as guidelines for their use for the prevention of migraine are presented in this review article.
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| format | Article |
| id | doaj-art-e97a56f65bb74693a1a25baba984a91b |
| institution | Kabale University |
| issn | 1392-3064 2424-5917 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Neurologijos seminarai |
| spelling | doaj-art-e97a56f65bb74693a1a25baba984a91b2025-01-20T18:22:54ZengVilnius University PressNeurologijos seminarai1392-30642424-59172019-12-01234(82)10.29014/ns.2019.24New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptorK. Ryliškienė 0D. Jatužis 1A. Vaitkus 2Vilnius University, LithuaniaVilnius University, LithuaniaLithuanian University of Health Sciences Migraine is a long-lasting neurological disorder with significant negative impact not only on the patient’s life, but also on society. For many years, preventive treatment of migraine included drugs developed for diseases other than migraine such as hypertension, depression, and epilepsy. During the last decade, blocking calcitonin gene-related peptide (CGRP) has emerged as a possible mechanism for preventing migraine attacks, and monoclonal antibodies against CGRP and its receptor for the specific migraine prophylaxis have been developed. Results of clinical trials, safety and tolerability of the new class of drugs as well as guidelines for their use for the prevention of migraine are presented in this review article. https://www.journals.vu.lt/neurologijos_seminarai/article/view/27765migraineeconomic burdenpreventionCGRPCGRP receptormonoclonal antibodies |
| spellingShingle | K. Ryliškienė D. Jatužis A. Vaitkus New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptor Neurologijos seminarai migraine economic burden prevention CGRP CGRP receptor monoclonal antibodies |
| title | New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptor |
| title_full | New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptor |
| title_fullStr | New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptor |
| title_full_unstemmed | New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptor |
| title_short | New specific migraine prevention: monoclonal antibodies against calcitonin gene-related peptide and its receptor |
| title_sort | new specific migraine prevention monoclonal antibodies against calcitonin gene related peptide and its receptor |
| topic | migraine economic burden prevention CGRP CGRP receptor monoclonal antibodies |
| url | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27765 |
| work_keys_str_mv | AT kryliskiene newspecificmigrainepreventionmonoclonalantibodiesagainstcalcitoningenerelatedpeptideanditsreceptor AT djatuzis newspecificmigrainepreventionmonoclonalantibodiesagainstcalcitoningenerelatedpeptideanditsreceptor AT avaitkus newspecificmigrainepreventionmonoclonalantibodiesagainstcalcitoningenerelatedpeptideanditsreceptor |