Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study
Situs anomalies, including situs inversus and situs ambiguous (SAMB), are rare congenital conditions typically noted in pediatric populations, with SAMB being particularly uncommon in adults. This case study addresses the incidental discovery of situs ambiguous with polysplenia in a 65-year-old man...
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MDPI AG
2024-12-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/60/12/2010 |
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| author | Pavel E. Stanchev Mariya Dimitrova Desislava Makakova Boris Tilov |
| author_facet | Pavel E. Stanchev Mariya Dimitrova Desislava Makakova Boris Tilov |
| author_sort | Pavel E. Stanchev |
| collection | DOAJ |
| description | Situs anomalies, including situs inversus and situs ambiguous (SAMB), are rare congenital conditions typically noted in pediatric populations, with SAMB being particularly uncommon in adults. This case study addresses the incidental discovery of situs ambiguous with polysplenia in a 65-year-old man evaluated for suspected adrenal adenoma. The patient’s medical history included benign prostatic hyperplasia and tuberculous pleurisy. Methods included a thorough physical examination and laboratory tests, which showed normal cortisol levels and ACTH rhythm. Contrast-enhanced CT imaging revealed multiple spleens near the right adrenal region, altered liver positioning, a truncated pancreas, and a right-sided stomach, while the right adrenal gland was not visualized. Notably, the patient exhibited minimal symptoms despite these significant anatomical anomalies. The findings underscore the rarity of situs ambiguous in adults and its unexpected association with endocrine pathology. This case highlights the importance of comprehensive imaging and a multidisciplinary approach in managing patients with unusual anatomical presentations. It suggests that situs anomalies may be more prevalent in adult populations than previously recognized and emphasizes the need for increased clinical awareness and evaluation in similar cases. |
| format | Article |
| id | doaj-art-e97948d03e624d5ba41c42feb05df981 |
| institution | DOAJ |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj-art-e97948d03e624d5ba41c42feb05df9812025-08-20T02:56:56ZengMDPI AGMedicina1010-660X1648-91442024-12-016012201010.3390/medicina60122010Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case StudyPavel E. Stanchev0Mariya Dimitrova1Desislava Makakova2Boris Tilov3Clinic of Endocrinology and Metabolic Diseases, St. George University Hospital, Medical University of Plovdiv, 4002 Plovdiv, BulgariaDepartment of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University of Plovdiv, 4002 Plovdiv, BulgariaDepartment of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University of Plovdiv, 4002 Plovdiv, BulgariaMedical College, Medical University of Plovdiv, 4002 Plovdiv, BulgariaSitus anomalies, including situs inversus and situs ambiguous (SAMB), are rare congenital conditions typically noted in pediatric populations, with SAMB being particularly uncommon in adults. This case study addresses the incidental discovery of situs ambiguous with polysplenia in a 65-year-old man evaluated for suspected adrenal adenoma. The patient’s medical history included benign prostatic hyperplasia and tuberculous pleurisy. Methods included a thorough physical examination and laboratory tests, which showed normal cortisol levels and ACTH rhythm. Contrast-enhanced CT imaging revealed multiple spleens near the right adrenal region, altered liver positioning, a truncated pancreas, and a right-sided stomach, while the right adrenal gland was not visualized. Notably, the patient exhibited minimal symptoms despite these significant anatomical anomalies. The findings underscore the rarity of situs ambiguous in adults and its unexpected association with endocrine pathology. This case highlights the importance of comprehensive imaging and a multidisciplinary approach in managing patients with unusual anatomical presentations. It suggests that situs anomalies may be more prevalent in adult populations than previously recognized and emphasizes the need for increased clinical awareness and evaluation in similar cases.https://www.mdpi.com/1648-9144/60/12/2010situs ambiguouspolyspleniaadrenal adenomacongenital anomaliesendocrinologyadult situs inversus |
| spellingShingle | Pavel E. Stanchev Mariya Dimitrova Desislava Makakova Boris Tilov Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study Medicina situs ambiguous polysplenia adrenal adenoma congenital anomalies endocrinology adult situs inversus |
| title | Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study |
| title_full | Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study |
| title_fullStr | Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study |
| title_full_unstemmed | Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study |
| title_short | Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study |
| title_sort | exploring the differential diagnosis of adrenal adenoma in the context of situs ambiguous a clinical case study |
| topic | situs ambiguous polysplenia adrenal adenoma congenital anomalies endocrinology adult situs inversus |
| url | https://www.mdpi.com/1648-9144/60/12/2010 |
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