Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm derived from odontogenic epithelial remnants in the central jaw bone. Most PIOSCCs originate from odontogenic cysts with a nonkeratinized epithelial lining, especially from radicular/residual and dentigerous cysts. Th...

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Main Authors: Kentaro Kikuchi, Fumio Ide, Shota Takizawa, Seiji Suzuki, Hideaki Sakashita, Tie-Jun Li, Kaoru Kusama
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2018/7959230
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author Kentaro Kikuchi
Fumio Ide
Shota Takizawa
Seiji Suzuki
Hideaki Sakashita
Tie-Jun Li
Kaoru Kusama
author_facet Kentaro Kikuchi
Fumio Ide
Shota Takizawa
Seiji Suzuki
Hideaki Sakashita
Tie-Jun Li
Kaoru Kusama
author_sort Kentaro Kikuchi
collection DOAJ
description Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm derived from odontogenic epithelial remnants in the central jaw bone. Most PIOSCCs originate from odontogenic cysts with a nonkeratinized epithelial lining, especially from radicular/residual and dentigerous cysts. There have been few reports of PIOSCCs derived from the odontogenic keratocyst (OKC), particularly those describing pathological features at the initial stage. The diagnosis of PIOSCC is difficult and based on exclusion of other carcinomas, including metastatic tumors from other primary sites. Here, we report an extremely rare case of initial-stage PIOSCC derived from the OKC with unusual keratoameloblastomatous change of the maxilla.
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institution Kabale University
issn 2090-6765
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language English
publishDate 2018-01-01
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record_format Article
series Case Reports in Otolaryngology
spelling doaj-art-e977a1c215b847df95d0adf00b5842092025-02-03T00:59:27ZengWileyCase Reports in Otolaryngology2090-67652090-67732018-01-01201810.1155/2018/79592307959230Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature DiscussionKentaro Kikuchi0Fumio Ide1Shota Takizawa2Seiji Suzuki3Hideaki Sakashita4Tie-Jun Li5Kaoru Kusama6Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, JapanDivision of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, JapanSecond Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, JapanSecond Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, JapanSecond Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, JapanDepartment of Oral Pathology, Peking University School of Stomatology, 22 South Zhongguancun Avenue, Haidian District, Beijing 100081, ChinaDivision of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, JapanPrimary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm derived from odontogenic epithelial remnants in the central jaw bone. Most PIOSCCs originate from odontogenic cysts with a nonkeratinized epithelial lining, especially from radicular/residual and dentigerous cysts. There have been few reports of PIOSCCs derived from the odontogenic keratocyst (OKC), particularly those describing pathological features at the initial stage. The diagnosis of PIOSCC is difficult and based on exclusion of other carcinomas, including metastatic tumors from other primary sites. Here, we report an extremely rare case of initial-stage PIOSCC derived from the OKC with unusual keratoameloblastomatous change of the maxilla.http://dx.doi.org/10.1155/2018/7959230
spellingShingle Kentaro Kikuchi
Fumio Ide
Shota Takizawa
Seiji Suzuki
Hideaki Sakashita
Tie-Jun Li
Kaoru Kusama
Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion
Case Reports in Otolaryngology
title Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion
title_full Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion
title_fullStr Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion
title_full_unstemmed Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion
title_short Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion
title_sort initial stage primary intraosseous squamous cell carcinoma derived from odontogenic keratocyst with unusual keratoameloblastomatous change of the maxilla a case report and literature discussion
url http://dx.doi.org/10.1155/2018/7959230
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