Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in Japan

Objectives To examine the association between body temperature (BT) on hospital arrival and in-hospital mortality among paediatric trauma patients.Design A retrospective cohort study.Setting Japan Trauma Data Bank (JTDB, which is a nationwide, prospective, observational trauma registry with data fro...

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Main Authors: Tetsuhisa Kitamura, Yohei Okada, Ryoji Iiduka, Wataru Ishii, Asami Okada, Hiromichi Narumiya, Toshio Osamura
Format: Article
Language:English
Published: BMJ Publishing Group 2020-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/11/e033822.full
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author Tetsuhisa Kitamura
Yohei Okada
Ryoji Iiduka
Wataru Ishii
Asami Okada
Hiromichi Narumiya
Toshio Osamura
author_facet Tetsuhisa Kitamura
Yohei Okada
Ryoji Iiduka
Wataru Ishii
Asami Okada
Hiromichi Narumiya
Toshio Osamura
author_sort Tetsuhisa Kitamura
collection DOAJ
description Objectives To examine the association between body temperature (BT) on hospital arrival and in-hospital mortality among paediatric trauma patients.Design A retrospective cohort study.Setting Japan Trauma Data Bank (JTDB, which is a nationwide, prospective, observational trauma registry with data from 235 hospitals).Participants Paediatric trauma patients <16 years old who were transferred directly from the scene of injury to the hospital and registered in the JTDB from January 2004 to December 2017 were included. We excluded patients >16 years old and those who developed cardiac arrest before or on hospital arrival.Primary outcome The association between BT on hospital arrival and in-hospital mortality. We conducted multivariate logistic regression analyses to calculate the adjusted ORs, with their 95% CIs, of the association between BT and in-hospital mortality.Results A total of 9012 patients were included (median age: 9 years (IQR, 6.0–13.0 years), mortality: 2.5% (mortality number was 226 in total 9012 patients)). In the multivariate logistic regression analysis, the corresponding adjusted ORs of BT <36.0°C and BT ≥37.0°C, relative to a BT of 36°C–36.9°C, for in-hospital mortality were 2.83 (95% CI: 1.85 to 4.33) and 0.93 (95% CI: 0.53 to 1.63), respectively.Conclusions In paediatric patients with hypothermia (BT <36.0°C) on hospital arrival, a clear association with in-hospital mortality was observed; no such association was observed between higher BT values (≥37.0°C) and outcomes.
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spelling doaj-art-e964a76ad22d4423a73e91b20beb53092025-08-20T02:28:32ZengBMJ Publishing GroupBMJ Open2044-60552020-11-01101110.1136/bmjopen-2019-033822Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in JapanTetsuhisa Kitamura0Yohei Okada1Ryoji Iiduka2Wataru Ishii3Asami Okada4Hiromichi Narumiya5Toshio Osamura62 Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Suita, JapanPrimary Care and Emergency Medicine, Kyoto University, Kyoto, Japan3 Emergency and Critical Care Medicine, Japanese Red Cross Society, Kyoto Daini Hospital, Kyoto, Japan3 Emergency and Critical Care Medicine, Japanese Red Cross Society, Kyoto Daini Hospital, Kyoto, JapanEmergency and Critical Care Medicine, Kyoto Daini Sekijuji Byoin, Kyoto, JapanEmergency and Critical Care Medicine, Kyoto Daini Sekijuji Byoin, Kyoto, JapanDepartment of Pediatrics, Kyoto Daini Sekijuji Byoin, Kyoto, JapanObjectives To examine the association between body temperature (BT) on hospital arrival and in-hospital mortality among paediatric trauma patients.Design A retrospective cohort study.Setting Japan Trauma Data Bank (JTDB, which is a nationwide, prospective, observational trauma registry with data from 235 hospitals).Participants Paediatric trauma patients <16 years old who were transferred directly from the scene of injury to the hospital and registered in the JTDB from January 2004 to December 2017 were included. We excluded patients >16 years old and those who developed cardiac arrest before or on hospital arrival.Primary outcome The association between BT on hospital arrival and in-hospital mortality. We conducted multivariate logistic regression analyses to calculate the adjusted ORs, with their 95% CIs, of the association between BT and in-hospital mortality.Results A total of 9012 patients were included (median age: 9 years (IQR, 6.0–13.0 years), mortality: 2.5% (mortality number was 226 in total 9012 patients)). In the multivariate logistic regression analysis, the corresponding adjusted ORs of BT <36.0°C and BT ≥37.0°C, relative to a BT of 36°C–36.9°C, for in-hospital mortality were 2.83 (95% CI: 1.85 to 4.33) and 0.93 (95% CI: 0.53 to 1.63), respectively.Conclusions In paediatric patients with hypothermia (BT <36.0°C) on hospital arrival, a clear association with in-hospital mortality was observed; no such association was observed between higher BT values (≥37.0°C) and outcomes.https://bmjopen.bmj.com/content/10/11/e033822.full
spellingShingle Tetsuhisa Kitamura
Yohei Okada
Ryoji Iiduka
Wataru Ishii
Asami Okada
Hiromichi Narumiya
Toshio Osamura
Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in Japan
BMJ Open
title Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in Japan
title_full Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in Japan
title_fullStr Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in Japan
title_full_unstemmed Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in Japan
title_short Association of body temperature with in-hospital mortality among paediatric trauma patients: an analysis of a nationwide observational trauma database in Japan
title_sort association of body temperature with in hospital mortality among paediatric trauma patients an analysis of a nationwide observational trauma database in japan
url https://bmjopen.bmj.com/content/10/11/e033822.full
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