Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population

Background. Celiac disease (CD) and inflammatory bowel disease (IBD) involve inflammation of the gastrointestinal lumen, which environmental, genetic, and immunological factors have a role in their pathogenesis. The prevalence of celiac disease in IBD ranges from 0% to 14%. In this study, our aim wa...

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Main Authors: Göksel Bengi, Musa Cıvak, Mesut Akarsu, Müjde Soytürk, Ender Ellidokuz, Ömer Topalak, Hale Akpınar
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2019/6272098
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author Göksel Bengi
Musa Cıvak
Mesut Akarsu
Müjde Soytürk
Ender Ellidokuz
Ömer Topalak
Hale Akpınar
author_facet Göksel Bengi
Musa Cıvak
Mesut Akarsu
Müjde Soytürk
Ender Ellidokuz
Ömer Topalak
Hale Akpınar
author_sort Göksel Bengi
collection DOAJ
description Background. Celiac disease (CD) and inflammatory bowel disease (IBD) involve inflammation of the gastrointestinal lumen, which environmental, genetic, and immunological factors have a role in their pathogenesis. The prevalence of celiac disease in IBD ranges from 0% to 14%. In this study, our aim was to determine the prevalence of CD in IBD patients followed by us who are attending the hospital or outpatient clinic over a period of time of seven years. Methods. Seven hundred and fifty nine patients (425 M, 334 F, mean age: 46.75, 396 ulcerative colitis (UC), 363 Crohn’s disease (CrD)) diagnosed and followed up for IBD between January 2009 and July 2016 were evaluated retrospectively, and clinical, demographic, laboratory, and endoscopic data were collected. Results. CD was investigated in 79 (%10.4) inflammatory bowel disease patients according to symptoms, and in 5.06% (n=4) of them, we diagnosed CD. The most common indication for investigating for CD was iron deficiency anemia unreponsive to iron supplementation. Conclusions. We did not find an increased prevalance of celiac disease in Turkish IBD patients in this study. In the presence of refractory iron deficiency anemia without any other cause in IBD patients, investigations for celiac disease should be considered.
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spelling doaj-art-e961be4b4f3b484eb8aca4a3650b3e432025-08-20T02:22:06ZengWileyGastroenterology Research and Practice1687-61211687-630X2019-01-01201910.1155/2019/62720986272098Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish PopulationGöksel Bengi0Musa Cıvak1Mesut Akarsu2Müjde Soytürk3Ender Ellidokuz4Ömer Topalak5Hale Akpınar6Gastroenterology Unit, Department of Internal Medicine, Dokuz Eylül University, İzmir, TurkeyDepartment of Internal Medicine, Dokuz Eylül University, İzmir, TurkeyGastroenterology Unit, Department of Internal Medicine, Dokuz Eylül University, İzmir, TurkeyGastroenterology Unit, Department of Internal Medicine, Dokuz Eylül University, İzmir, TurkeyGastroenterology Unit, Department of Internal Medicine, Dokuz Eylül University, İzmir, TurkeyGastroenterology Unit, Department of Internal Medicine, Dokuz Eylül University, İzmir, TurkeyGastroenterology Unit, Department of Internal Medicine, Dokuz Eylül University, İzmir, TurkeyBackground. Celiac disease (CD) and inflammatory bowel disease (IBD) involve inflammation of the gastrointestinal lumen, which environmental, genetic, and immunological factors have a role in their pathogenesis. The prevalence of celiac disease in IBD ranges from 0% to 14%. In this study, our aim was to determine the prevalence of CD in IBD patients followed by us who are attending the hospital or outpatient clinic over a period of time of seven years. Methods. Seven hundred and fifty nine patients (425 M, 334 F, mean age: 46.75, 396 ulcerative colitis (UC), 363 Crohn’s disease (CrD)) diagnosed and followed up for IBD between January 2009 and July 2016 were evaluated retrospectively, and clinical, demographic, laboratory, and endoscopic data were collected. Results. CD was investigated in 79 (%10.4) inflammatory bowel disease patients according to symptoms, and in 5.06% (n=4) of them, we diagnosed CD. The most common indication for investigating for CD was iron deficiency anemia unreponsive to iron supplementation. Conclusions. We did not find an increased prevalance of celiac disease in Turkish IBD patients in this study. In the presence of refractory iron deficiency anemia without any other cause in IBD patients, investigations for celiac disease should be considered.http://dx.doi.org/10.1155/2019/6272098
spellingShingle Göksel Bengi
Musa Cıvak
Mesut Akarsu
Müjde Soytürk
Ender Ellidokuz
Ömer Topalak
Hale Akpınar
Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population
Gastroenterology Research and Practice
title Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population
title_full Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population
title_fullStr Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population
title_full_unstemmed Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population
title_short Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population
title_sort prevalance of celiac disease in patients with inflammatory bowel disease in turkish population
url http://dx.doi.org/10.1155/2019/6272098
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AT mujdesoyturk prevalanceofceliacdiseaseinpatientswithinflammatoryboweldiseaseinturkishpopulation
AT enderellidokuz prevalanceofceliacdiseaseinpatientswithinflammatoryboweldiseaseinturkishpopulation
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