Battle of the strategies: diet versus drug therapy for gout

The best results in combating gout are achieved through a combination of diet and drug therapy. Urate-lowering therapy, which includes febuxostat, has been shown to be more effective and convenient than diet when it comes to achieving and maintaining target uric acid (UA) levels in gout patients. Fe...

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Main Authors: O. V. Zhelyabina, M. S. Eliseev, A. M. Lila
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2024-06-01
Series:Современная ревматология
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Online Access:https://mrj.ima-press.net/mrj/article/view/1597
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author O. V. Zhelyabina
M. S. Eliseev
A. M. Lila
author_facet O. V. Zhelyabina
M. S. Eliseev
A. M. Lila
author_sort O. V. Zhelyabina
collection DOAJ
description The best results in combating gout are achieved through a combination of diet and drug therapy. Urate-lowering therapy, which includes febuxostat, has been shown to be more effective and convenient than diet when it comes to achieving and maintaining target uric acid (UA) levels in gout patients. Febuxostat, a xanthine oxidase inhibitor, helps to reduce UA levels in the blood by blocking its formation. This helps prevent the deposition of urate crystals in joints and tissues and reduces the frequency and severity of gout attacks. At the same time, a diet of low purine foods may also have some effect on UA levels. Diet can improve the results of drug treatment by reducing the need for medications and minimizing the risk of side effects. However, without adequate drug therapy, diet will not produce the desired results. Therefore, febuxostat remains the preferred urate-lowering treatment option for gout, especially given its proven efficacy in these patients.
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series Современная ревматология
spelling doaj-art-e95e879543714fc3bf580611852d6b8f2025-08-20T03:01:21ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2024-06-0118311412110.14412/1996-7012-2024-3-114-1212693Battle of the strategies: diet versus drug therapy for goutO. V. Zhelyabina0M. S. Eliseev1A. M. Lila2V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyThe best results in combating gout are achieved through a combination of diet and drug therapy. Urate-lowering therapy, which includes febuxostat, has been shown to be more effective and convenient than diet when it comes to achieving and maintaining target uric acid (UA) levels in gout patients. Febuxostat, a xanthine oxidase inhibitor, helps to reduce UA levels in the blood by blocking its formation. This helps prevent the deposition of urate crystals in joints and tissues and reduces the frequency and severity of gout attacks. At the same time, a diet of low purine foods may also have some effect on UA levels. Diet can improve the results of drug treatment by reducing the need for medications and minimizing the risk of side effects. However, without adequate drug therapy, diet will not produce the desired results. Therefore, febuxostat remains the preferred urate-lowering treatment option for gout, especially given its proven efficacy in these patients.https://mrj.ima-press.net/mrj/article/view/1597goutdieturic acidfebuxostat
spellingShingle O. V. Zhelyabina
M. S. Eliseev
A. M. Lila
Battle of the strategies: diet versus drug therapy for gout
Современная ревматология
gout
diet
uric acid
febuxostat
title Battle of the strategies: diet versus drug therapy for gout
title_full Battle of the strategies: diet versus drug therapy for gout
title_fullStr Battle of the strategies: diet versus drug therapy for gout
title_full_unstemmed Battle of the strategies: diet versus drug therapy for gout
title_short Battle of the strategies: diet versus drug therapy for gout
title_sort battle of the strategies diet versus drug therapy for gout
topic gout
diet
uric acid
febuxostat
url https://mrj.ima-press.net/mrj/article/view/1597
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AT mseliseev battleofthestrategiesdietversusdrugtherapyforgout
AT amlila battleofthestrategiesdietversusdrugtherapyforgout