Impact of the counts density of calibration image and the image reconstruction parameters in 131I SPECT image quantification

Iodine-131 (131I) has been used for diagnosis and therapy in Nuclear Medicine Centers in Brazil for more than 50 years. The present study aims to investigate the impact of the counts density and the reconstruction parameters in the calibration factor determination and  in the image quantification, c...

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Main Authors: Samira Marques Carvalho, Ana Paula Marques Costa, Celso Dario Ramos, Sérgio Querino Brunetto, Daniel Alexandre Baptista Bonifácio
Format: Article
Language:English
Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 2018-01-01
Series:Brazilian Journal of Radiation Sciences
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Online Access:https://bjrs.org.br/revista/index.php/REVISTA/article/view/332
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author Samira Marques Carvalho
Ana Paula Marques Costa
Celso Dario Ramos
Sérgio Querino Brunetto
Daniel Alexandre Baptista Bonifácio
author_facet Samira Marques Carvalho
Ana Paula Marques Costa
Celso Dario Ramos
Sérgio Querino Brunetto
Daniel Alexandre Baptista Bonifácio
author_sort Samira Marques Carvalho
collection DOAJ
description Iodine-131 (131I) has been used for diagnosis and therapy in Nuclear Medicine Centers in Brazil for more than 50 years. The present study aims to investigate the impact of the counts density and the reconstruction parameters in the calibration factor determination and  in the image quantification, considering the reality of Brazilian dosimetry studies. For this task, images were quantified using calibration images with high and low counts density and reconstructed adopting two different parameters approaches, usually employed in patients images.  SPECT quantification results presented in this work follow other previous 131I SPECT studies and suggest that, due to the long time interval between the first e last image, as required by the Brazilian guideline, the image quantification accuracy can be improved if the counts density in calibration measurements is considered.
format Article
id doaj-art-e958245f159049a5a86f71821cbc2e20
institution DOAJ
issn 2319-0612
language English
publishDate 2018-01-01
publisher Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)
record_format Article
series Brazilian Journal of Radiation Sciences
spelling doaj-art-e958245f159049a5a86f71821cbc2e202025-08-20T02:50:59ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122018-01-016110.15392/bjrs.v6i1.332Impact of the counts density of calibration image and the image reconstruction parameters in 131I SPECT image quantificationSamira Marques Carvalho0Ana Paula Marques Costa1Celso Dario Ramos2Sérgio Querino Brunetto3Daniel Alexandre Baptista Bonifácio4Comissão Nacional de Energia NuclearServiço de Medicina Nuclear, SMN/HC-UNICAMPServiço de Medicina Nuclear, SMN/HC-UNICAMPCentro de Engenharia Biomédica, CEB/UNICAMPInstituto de Radioproteção e Dosimetria, IRD/CNENIodine-131 (131I) has been used for diagnosis and therapy in Nuclear Medicine Centers in Brazil for more than 50 years. The present study aims to investigate the impact of the counts density and the reconstruction parameters in the calibration factor determination and  in the image quantification, considering the reality of Brazilian dosimetry studies. For this task, images were quantified using calibration images with high and low counts density and reconstructed adopting two different parameters approaches, usually employed in patients images.  SPECT quantification results presented in this work follow other previous 131I SPECT studies and suggest that, due to the long time interval between the first e last image, as required by the Brazilian guideline, the image quantification accuracy can be improved if the counts density in calibration measurements is considered. https://bjrs.org.br/revista/index.php/REVISTA/article/view/332SPECTcalibrationuncertaintiesquantification accuracy.
spellingShingle Samira Marques Carvalho
Ana Paula Marques Costa
Celso Dario Ramos
Sérgio Querino Brunetto
Daniel Alexandre Baptista Bonifácio
Impact of the counts density of calibration image and the image reconstruction parameters in 131I SPECT image quantification
Brazilian Journal of Radiation Sciences
SPECT
calibration
uncertainties
quantification accuracy.
title Impact of the counts density of calibration image and the image reconstruction parameters in 131I SPECT image quantification
title_full Impact of the counts density of calibration image and the image reconstruction parameters in 131I SPECT image quantification
title_fullStr Impact of the counts density of calibration image and the image reconstruction parameters in 131I SPECT image quantification
title_full_unstemmed Impact of the counts density of calibration image and the image reconstruction parameters in 131I SPECT image quantification
title_short Impact of the counts density of calibration image and the image reconstruction parameters in 131I SPECT image quantification
title_sort impact of the counts density of calibration image and the image reconstruction parameters in 131i spect image quantification
topic SPECT
calibration
uncertainties
quantification accuracy.
url https://bjrs.org.br/revista/index.php/REVISTA/article/view/332
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