Synthesis and characterization of Zn-bionanocrystals: Revealing pH-time release dynamics of encapsulated Zn+2 ions for sustainable applications using response surface methodology
In India’s complex environmental landscape, zinc (Zn) deficiency poses a dual threat to human health and ecological balance. This study investigates the synthesis of stable Zn-bionanocrystals as a novel, eco-friendly approach to combat Zn deficiency and promote environmental sustainability. Employin...
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Elsevier
2025-01-01
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| Series: | Next Nanotechnology |
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| author | Sonam Sihag Ajay Pal Surbhi Sahewalla Vinod Saharan |
| author_facet | Sonam Sihag Ajay Pal Surbhi Sahewalla Vinod Saharan |
| author_sort | Sonam Sihag |
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| description | In India’s complex environmental landscape, zinc (Zn) deficiency poses a dual threat to human health and ecological balance. This study investigates the synthesis of stable Zn-bionanocrystals as a novel, eco-friendly approach to combat Zn deficiency and promote environmental sustainability. Employing characterization techniques like PSA, BET, FTIR, SEM, and TEM, the structural and morphological features of the Zn-bionanocrystals were evaluated. Key attributes included a hydrodynamic diameter of 374–396 nm (PDI 0.13–0.22), zeta-potential of + 39.7 to + 44.6 mV, and porous architecture. BET analysis showed a surface area of 16.04 m²/g and a pore volume of 0.181 cc/g, suggesting strong potential for environmental interactions. FTIR confirmed the presence of chemical modifications, while high encapsulation efficiency (84 %) and loading capacity (3.36 %) demonstrated the suitability of this system for green delivery applications. A systematic Zn²⁺ release study across pH values (1.0–7.0) and up to 216 h revealed controlled, pH- and time-dependent release behaviour, with maximum release at low pH (70.5 % at pH 1.0 vs. 4.92 % at pH 7.0) and sustained release over time (53.3 % at 216 h). These findings highlight the promise of Zn-bionanocrystals in addressing micronutrient deficiencies, advancing sustainable agriculture, and enhancing ecological resilience in the face of growing environmental pressures. |
| format | Article |
| id | doaj-art-e957f79ed02247edac483c2b94207aca |
| institution | Kabale University |
| issn | 2949-8295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
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| series | Next Nanotechnology |
| spelling | doaj-art-e957f79ed02247edac483c2b94207aca2025-08-20T03:58:36ZengElsevierNext Nanotechnology2949-82952025-01-01810022610.1016/j.nxnano.2025.100226Synthesis and characterization of Zn-bionanocrystals: Revealing pH-time release dynamics of encapsulated Zn+2 ions for sustainable applications using response surface methodologySonam Sihag0Ajay Pal1Surbhi Sahewalla2Vinod Saharan3Department of Biochemistry, College of Basic Sciences and Humanities, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana 125 004, India; Corresponding author.Department of Biochemistry, College of Basic Sciences and Humanities, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana 125 004, IndiaDepartment of Biochemistry, College of Basic Sciences and Humanities, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana 125 004, IndiaDepartment of Molecular Biology and Biotechnology, Rajasthan College of Agriculture, Maharana Pratap University of Agriculture and Technology, Udaipur, Rajasthan 313 001, IndiaIn India’s complex environmental landscape, zinc (Zn) deficiency poses a dual threat to human health and ecological balance. This study investigates the synthesis of stable Zn-bionanocrystals as a novel, eco-friendly approach to combat Zn deficiency and promote environmental sustainability. Employing characterization techniques like PSA, BET, FTIR, SEM, and TEM, the structural and morphological features of the Zn-bionanocrystals were evaluated. Key attributes included a hydrodynamic diameter of 374–396 nm (PDI 0.13–0.22), zeta-potential of + 39.7 to + 44.6 mV, and porous architecture. BET analysis showed a surface area of 16.04 m²/g and a pore volume of 0.181 cc/g, suggesting strong potential for environmental interactions. FTIR confirmed the presence of chemical modifications, while high encapsulation efficiency (84 %) and loading capacity (3.36 %) demonstrated the suitability of this system for green delivery applications. A systematic Zn²⁺ release study across pH values (1.0–7.0) and up to 216 h revealed controlled, pH- and time-dependent release behaviour, with maximum release at low pH (70.5 % at pH 1.0 vs. 4.92 % at pH 7.0) and sustained release over time (53.3 % at 216 h). These findings highlight the promise of Zn-bionanocrystals in addressing micronutrient deficiencies, advancing sustainable agriculture, and enhancing ecological resilience in the face of growing environmental pressures.http://www.sciencedirect.com/science/article/pii/S2949829525000956NanotechnologyZn-bionanocrystalsResponse surface methodologyRelease kineticsZinc encapsulationControlled release |
| spellingShingle | Sonam Sihag Ajay Pal Surbhi Sahewalla Vinod Saharan Synthesis and characterization of Zn-bionanocrystals: Revealing pH-time release dynamics of encapsulated Zn+2 ions for sustainable applications using response surface methodology Next Nanotechnology Nanotechnology Zn-bionanocrystals Response surface methodology Release kinetics Zinc encapsulation Controlled release |
| title | Synthesis and characterization of Zn-bionanocrystals: Revealing pH-time release dynamics of encapsulated Zn+2 ions for sustainable applications using response surface methodology |
| title_full | Synthesis and characterization of Zn-bionanocrystals: Revealing pH-time release dynamics of encapsulated Zn+2 ions for sustainable applications using response surface methodology |
| title_fullStr | Synthesis and characterization of Zn-bionanocrystals: Revealing pH-time release dynamics of encapsulated Zn+2 ions for sustainable applications using response surface methodology |
| title_full_unstemmed | Synthesis and characterization of Zn-bionanocrystals: Revealing pH-time release dynamics of encapsulated Zn+2 ions for sustainable applications using response surface methodology |
| title_short | Synthesis and characterization of Zn-bionanocrystals: Revealing pH-time release dynamics of encapsulated Zn+2 ions for sustainable applications using response surface methodology |
| title_sort | synthesis and characterization of zn bionanocrystals revealing ph time release dynamics of encapsulated zn 2 ions for sustainable applications using response surface methodology |
| topic | Nanotechnology Zn-bionanocrystals Response surface methodology Release kinetics Zinc encapsulation Controlled release |
| url | http://www.sciencedirect.com/science/article/pii/S2949829525000956 |
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