Soil microbes in the Tibetan Plateau degrade polyvinyl chloride and harbor novel dehalogenase SerB

Polyvinyl chloride (PVC) stands as the third most widely produced synthetic polymer plastic. However, investigations into its microbial degradation significantly trail those of polyethylene (PE) and polystyrene (PS). Here, this study enriched a PVC-degrading consortium DC from the soil microbes of T...

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Main Authors: Yuchao Jiang, Baotong Fu, Wei-Min Wu, Chunxiu Zhou, Aman Khan, Guorui Zhang, El-Sayed Salama, Byong-Hun Jeon, Maha Awjan Alreshidi, Chunjie Li, Huawen Han, Xiangkai Li
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Environment International
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Online Access:http://www.sciencedirect.com/science/article/pii/S0160412025004593
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author Yuchao Jiang
Baotong Fu
Wei-Min Wu
Chunxiu Zhou
Aman Khan
Guorui Zhang
El-Sayed Salama
Byong-Hun Jeon
Maha Awjan Alreshidi
Chunjie Li
Huawen Han
Xiangkai Li
author_facet Yuchao Jiang
Baotong Fu
Wei-Min Wu
Chunxiu Zhou
Aman Khan
Guorui Zhang
El-Sayed Salama
Byong-Hun Jeon
Maha Awjan Alreshidi
Chunjie Li
Huawen Han
Xiangkai Li
author_sort Yuchao Jiang
collection DOAJ
description Polyvinyl chloride (PVC) stands as the third most widely produced synthetic polymer plastic. However, investigations into its microbial degradation significantly trail those of polyethylene (PE) and polystyrene (PS). Here, this study enriched a PVC-degrading consortium DC from the soil microbes of Tibet Plateau grasslands, confirming the formation of long-chain alkanes and the release of chloride ions via GC–MS and ion chromatography analysis. The response of DC to synthetic polymer PVC and natural polymer lignin revealed resistant polymer-response Burkholderia, opportunistic polymer-response Rhodococcus, and sensitive polymer-response Dyella. These PVC-degrading bacteria exist in 432 datasets of alpine meadows. Metaproteomic analysis highlighted distinct enzymatic profiles between PVC-DC and lignin-DC, with 298 proteins associated with PVC degradation compared to 123 proteins linked to lignin. Six key protein categories, including dehalogenase, peroxidase, monooxygenase, dioxygenase, esterase, and dehydrogenase, were involved in PVC degradation. An upregulated dehalogenase SerB from Rhodococcus, belonging to the clade of phosphoserine phosphatase, displayed proficiency in degrading chloroacetic acid and PVC films via hydrolytic dehalogenation. Furthermore, global metagenomic analysis from 38 datasets underscored the prevalence of dehalogenases and related enzymes in grasslands. This study elucidates the microbial responses and enzymatic pathways in PVC degradation, emphasizing the abundance of PVC-degrading enzymes in alpine ecosystems.
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institution Kabale University
issn 0160-4120
language English
publishDate 2025-08-01
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spelling doaj-art-e952b1656c854765a99bb499523027322025-08-20T03:33:04ZengElsevierEnvironment International0160-41202025-08-0120210970810.1016/j.envint.2025.109708Soil microbes in the Tibetan Plateau degrade polyvinyl chloride and harbor novel dehalogenase SerBYuchao Jiang0Baotong Fu1Wei-Min Wu2Chunxiu Zhou3Aman Khan4Guorui Zhang5El-Sayed Salama6Byong-Hun Jeon7Maha Awjan Alreshidi8Chunjie Li9Huawen Han10Xiangkai Li11Centre for Grassland Microbiome, State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems, College of Pastoral Agricultural Science and Technology, Lanzhou University, Lanzhou 730000, China; Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, Gansu 730000, ChinaCentre for Grassland Microbiome, State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems, College of Pastoral Agricultural Science and Technology, Lanzhou University, Lanzhou 730000, ChinaDepartment of Civil and Environmental Engineering, William & Cloy Codiga Resource Recovery Center, Stanford University, Stanford, CA 94305, United StatesCentre for Grassland Microbiome, State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems, College of Pastoral Agricultural Science and Technology, Lanzhou University, Lanzhou 730000, ChinaKey Laboratory of Saline-Alkali Vegetation Ecology Restoration, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, ChinaCentre for Grassland Microbiome, State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems, College of Pastoral Agricultural Science and Technology, Lanzhou University, Lanzhou 730000, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Lanzhou University, Lanzhou 730000 Gansu, ChinaDepartment of Earth Resources and Environmental Engineering, Hanyang University, Seoul 04763, South KoreaDepartment of Chemistry, College of Science, University of Ha’il, Ha’il 81451, Saudi ArabiaCentre for Grassland Microbiome, State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems, College of Pastoral Agricultural Science and Technology, Lanzhou University, Lanzhou 730000, China; Corresponding authors.Centre for Grassland Microbiome, State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems, College of Pastoral Agricultural Science and Technology, Lanzhou University, Lanzhou 730000, China; Corresponding authors.Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, Gansu 730000, ChinaPolyvinyl chloride (PVC) stands as the third most widely produced synthetic polymer plastic. However, investigations into its microbial degradation significantly trail those of polyethylene (PE) and polystyrene (PS). Here, this study enriched a PVC-degrading consortium DC from the soil microbes of Tibet Plateau grasslands, confirming the formation of long-chain alkanes and the release of chloride ions via GC–MS and ion chromatography analysis. The response of DC to synthetic polymer PVC and natural polymer lignin revealed resistant polymer-response Burkholderia, opportunistic polymer-response Rhodococcus, and sensitive polymer-response Dyella. These PVC-degrading bacteria exist in 432 datasets of alpine meadows. Metaproteomic analysis highlighted distinct enzymatic profiles between PVC-DC and lignin-DC, with 298 proteins associated with PVC degradation compared to 123 proteins linked to lignin. Six key protein categories, including dehalogenase, peroxidase, monooxygenase, dioxygenase, esterase, and dehydrogenase, were involved in PVC degradation. An upregulated dehalogenase SerB from Rhodococcus, belonging to the clade of phosphoserine phosphatase, displayed proficiency in degrading chloroacetic acid and PVC films via hydrolytic dehalogenation. Furthermore, global metagenomic analysis from 38 datasets underscored the prevalence of dehalogenases and related enzymes in grasslands. This study elucidates the microbial responses and enzymatic pathways in PVC degradation, emphasizing the abundance of PVC-degrading enzymes in alpine ecosystems.http://www.sciencedirect.com/science/article/pii/S0160412025004593PVCBiodegradationQinghai-Tibet PlateauDehalogenaseMetaproteomics
spellingShingle Yuchao Jiang
Baotong Fu
Wei-Min Wu
Chunxiu Zhou
Aman Khan
Guorui Zhang
El-Sayed Salama
Byong-Hun Jeon
Maha Awjan Alreshidi
Chunjie Li
Huawen Han
Xiangkai Li
Soil microbes in the Tibetan Plateau degrade polyvinyl chloride and harbor novel dehalogenase SerB
Environment International
PVC
Biodegradation
Qinghai-Tibet Plateau
Dehalogenase
Metaproteomics
title Soil microbes in the Tibetan Plateau degrade polyvinyl chloride and harbor novel dehalogenase SerB
title_full Soil microbes in the Tibetan Plateau degrade polyvinyl chloride and harbor novel dehalogenase SerB
title_fullStr Soil microbes in the Tibetan Plateau degrade polyvinyl chloride and harbor novel dehalogenase SerB
title_full_unstemmed Soil microbes in the Tibetan Plateau degrade polyvinyl chloride and harbor novel dehalogenase SerB
title_short Soil microbes in the Tibetan Plateau degrade polyvinyl chloride and harbor novel dehalogenase SerB
title_sort soil microbes in the tibetan plateau degrade polyvinyl chloride and harbor novel dehalogenase serb
topic PVC
Biodegradation
Qinghai-Tibet Plateau
Dehalogenase
Metaproteomics
url http://www.sciencedirect.com/science/article/pii/S0160412025004593
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