Large Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability Study

BackgroundAdequate health literacy has been shown to be important for the general health of a population. To address this, it is recommended that patient-targeted medical information is written at a sixth-grade reading level. To make well-informed decisions about their health...

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Main Authors: Reza Kianian, Deyu Sun, William Rojas-Carabali, Rupesh Agrawal, Edmund Tsui
Format: Article
Language:English
Published: JMIR Publications 2024-12-01
Series:Journal of Medical Internet Research
Online Access:https://www.jmir.org/2024/1/e59843
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author Reza Kianian
Deyu Sun
William Rojas-Carabali
Rupesh Agrawal
Edmund Tsui
author_facet Reza Kianian
Deyu Sun
William Rojas-Carabali
Rupesh Agrawal
Edmund Tsui
author_sort Reza Kianian
collection DOAJ
description BackgroundAdequate health literacy has been shown to be important for the general health of a population. To address this, it is recommended that patient-targeted medical information is written at a sixth-grade reading level. To make well-informed decisions about their health, patients may want to interact directly with peer-reviewed open access scientific articles. However, studies have shown that such text is often written with highly complex language above the levels that can be comprehended by the general population. Previously, we have published on the use of large language models (LLMs) in easing the readability of patient-targeted health information on the internet. In this study, we continue to explore the advantages of LLMs in patient education. ObjectiveThis study aimed to explore the use of LLMs, specifically ChatGPT (OpenAI), to enhance the readability of peer-reviewed scientific articles in the field of ophthalmology. MethodsA total of 12 open access, peer-reviewed papers published by the senior authors of this study (ET and RA) were selected. Readability was assessed using the Flesch-Kincaid Grade Level and Simple Measure of Gobbledygook tests. ChatGPT 4.0 was asked “I will give you the text of a peer-reviewed scientific paper. Considering that the recommended readability of the text is 6th grade, can you simplify the following text so that a layperson reading this text can fully comprehend it? - Insert Manuscript Text -”. Appropriateness was evaluated by the 2 uveitis-trained ophthalmologists. Statistical analysis was performed in Microsoft Excel. ResultsChatGPT significantly lowered the readability and length of the selected papers from 15th to 7th grade (P<.001) while generating responses that were deemed appropriate by expert ophthalmologists. ConclusionsLLMs show promise in improving health literacy by enhancing the accessibility of peer-reviewed scientific articles and allowing the general population to interact directly with medical literature.
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spelling doaj-art-e9452882c5424cfab66bf4f317ea5ce82024-12-24T18:00:30ZengJMIR PublicationsJournal of Medical Internet Research1438-88712024-12-0126e5984310.2196/59843Large Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability StudyReza Kianianhttps://orcid.org/0000-0002-2737-8818Deyu Sunhttps://orcid.org/0000-0003-4637-0763William Rojas-Carabalihttps://orcid.org/0000-0002-9976-8989Rupesh Agrawalhttps://orcid.org/0000-0002-6662-5850Edmund Tsuihttps://orcid.org/0000-0001-7532-9191 BackgroundAdequate health literacy has been shown to be important for the general health of a population. To address this, it is recommended that patient-targeted medical information is written at a sixth-grade reading level. To make well-informed decisions about their health, patients may want to interact directly with peer-reviewed open access scientific articles. However, studies have shown that such text is often written with highly complex language above the levels that can be comprehended by the general population. Previously, we have published on the use of large language models (LLMs) in easing the readability of patient-targeted health information on the internet. In this study, we continue to explore the advantages of LLMs in patient education. ObjectiveThis study aimed to explore the use of LLMs, specifically ChatGPT (OpenAI), to enhance the readability of peer-reviewed scientific articles in the field of ophthalmology. MethodsA total of 12 open access, peer-reviewed papers published by the senior authors of this study (ET and RA) were selected. Readability was assessed using the Flesch-Kincaid Grade Level and Simple Measure of Gobbledygook tests. ChatGPT 4.0 was asked “I will give you the text of a peer-reviewed scientific paper. Considering that the recommended readability of the text is 6th grade, can you simplify the following text so that a layperson reading this text can fully comprehend it? - Insert Manuscript Text -”. Appropriateness was evaluated by the 2 uveitis-trained ophthalmologists. Statistical analysis was performed in Microsoft Excel. ResultsChatGPT significantly lowered the readability and length of the selected papers from 15th to 7th grade (P<.001) while generating responses that were deemed appropriate by expert ophthalmologists. ConclusionsLLMs show promise in improving health literacy by enhancing the accessibility of peer-reviewed scientific articles and allowing the general population to interact directly with medical literature.https://www.jmir.org/2024/1/e59843
spellingShingle Reza Kianian
Deyu Sun
William Rojas-Carabali
Rupesh Agrawal
Edmund Tsui
Large Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability Study
Journal of Medical Internet Research
title Large Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability Study
title_full Large Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability Study
title_fullStr Large Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability Study
title_full_unstemmed Large Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability Study
title_short Large Language Models May Help Patients Understand Peer-Reviewed Scientific Articles About Ophthalmology: Development and Usability Study
title_sort large language models may help patients understand peer reviewed scientific articles about ophthalmology development and usability study
url https://www.jmir.org/2024/1/e59843
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