A stearate-rich diet and oleate restriction directly inhibit tumor growth via the unfolded protein response

A stearate-rich diet and oleate restriction directly inhibit tumor growth via the unfolded protein response

Abstract Fatty acids are known to have significant effects on the properties of cancer cells. Therefore, these compounds have been incorporated into therapeutic strategies. However, few studies have examined the effects of individual fatty acids and their interactions in depth. This study analyzed t...

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Main Authors: Jumpei Ogura, Koji Yamanoi, Kentaro Ishida, Eijiro Nakamura, Shinji Ito, Naoki Aoyama, Yuki Nakanishi, Toshi Menju, Kosuke Kawaguchi, Yuko Hosoe, Mana Taki, Ryusuke Murakami, Ken Yamaguchi, Junzo Hamanishi, Masaki Mandai
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01356-2
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