A Minimally Invasive Transthoracic Injection Technique for Reproducible Intrapleural Delivery in Mice

A Minimally Invasive Transthoracic Injection Technique for Reproducible Intrapleural Delivery in Mice

The development of standardised, reproducible preclinical models is essential for advancing pleural mesothelioma (PM) research. Here, we present a simple and reliable minimally invasive transthoracic intrapleural injection technique that could improve the efficiency of orthotopic PM model generation...

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Bibliographic Details
Main Authors: Sophie Rovers, Pooyeh Farahmand, Dana Liu, Louize Brants, Christophe Hermans, Dieter Peeters, Danielle McKinven, Jennifer Doig, Filip Lardon, Jan van Meerbeeck, Elly Marcq, Daniel J. Murphy, Evelien Smits
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Methods and Protocols
Subjects:
orthotopic models
intrapleural injection
pleural mesothelioma
transthoracic injection
minimally invasive methods
preclinical models
Online Access:https://www.mdpi.com/2409-9279/8/3/55
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