Exercise orchestrates systemic metabolic and neuroimmune homeostasis via the brain–muscle–liver axis to slow down aging and neurodegeneration: a narrative review

Abstract Aging is a systemic process marked by progressive multi-organ dysfunction, metabolic dysregulation, and chronic low-grade inflammation ("inflammaging"), which collectively drive neurodegenerative diseases such as Alzheimer’s Disease (AD) and Parkinson’s Disease (PD). Emerging evid...

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Bibliographic Details
Main Authors: Jianda Kong, Yingao Xie, Rao Fan, Qinglu Wang, Ying Luo, Panpan Dong
Format: Article
Language:English
Published: BMC 2025-06-01
Series:European Journal of Medical Research
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Online Access:https://doi.org/10.1186/s40001-025-02751-9
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