Exploring hydrophilic sequence space to search for uncharted foldable proteins by AlphaFold2

Proteins typically fold into unique three-dimensional structures largely driven by interactions between hydrophobic amino acids. This understanding has helped improve our knowledge of protein folding. However, recent research has shown an exception to this idea, demonstrating that specific threonine...

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Bibliographic Details
Main Authors: Naoki Tomita, Hiroki Onoda, Leonard M. G. Chavas, George Chikenji
Format: Article
Language:English
Published: The Biophysical Society of Japan 2025-03-01
Series:Biophysics and Physicobiology
Subjects:
Online Access:https://doi.org/10.2142/biophysico.bppb-v22.0005
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