Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis
Atopic dermatitis (AD) is a multifactorial inflammatory skin disease. Its pathogenetic basis is epidermal barrier dysfunction, immune system dysregulation, as well as skin microbiome diversity decrease that occurs due to genetic predisposition. Considering these factors, the skin of patients with AD...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2022-11-01
|
| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/3033 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849242165460336640 |
|---|---|
| author | Nikolay N. Murashkin Roza Y. Nezhvedilova Dmitri V. Fedorov Roman V. Epishev Roman A. Ivanov Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova Lyudmila L. Rusakova |
| author_facet | Nikolay N. Murashkin Roza Y. Nezhvedilova Dmitri V. Fedorov Roman V. Epishev Roman A. Ivanov Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova Lyudmila L. Rusakova |
| author_sort | Nikolay N. Murashkin |
| collection | DOAJ |
| description | Atopic dermatitis (AD) is a multifactorial inflammatory skin disease. Its pathogenetic basis is epidermal barrier dysfunction, immune system dysregulation, as well as skin microbiome diversity decrease that occurs due to genetic predisposition. Considering these factors, the skin of patients with AD requires constant care and use of medications with active regenerative properties. The inclusion of anti-inflammatory components in the composition of modern emollients (zinc sulfate and sucralfate) is crucial for restoring the microbiome and immune mechanisms controlling the skin. This article presents data on pathogenetic applicability and clinical efficacy of emollients with anti-inflammatory compounds in patients with AD. |
| format | Article |
| id | doaj-art-e9236e53a6a94dd58200d0e8da0b6709 |
| institution | Kabale University |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2022-11-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-e9236e53a6a94dd58200d0e8da0b67092025-08-20T03:59:53Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352022-11-0121537838210.15690/vsp.v21i5.24572058Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic DermatitisNikolay N. Murashkin0Roza Y. Nezhvedilova1Dmitri V. Fedorov2Roman V. Epishev3Roman A. Ivanov4Alexander I. Materikin5Leonid A. Opryatin6Alena A. Savelova7Lyudmila L. Rusakova8National Medical Research Center of Children’s Health; Sechenov First Moscow State Medical University; Central State Medical Academy of Department of Presidential AffairsNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthAtopic dermatitis (AD) is a multifactorial inflammatory skin disease. Its pathogenetic basis is epidermal barrier dysfunction, immune system dysregulation, as well as skin microbiome diversity decrease that occurs due to genetic predisposition. Considering these factors, the skin of patients with AD requires constant care and use of medications with active regenerative properties. The inclusion of anti-inflammatory components in the composition of modern emollients (zinc sulfate and sucralfate) is crucial for restoring the microbiome and immune mechanisms controlling the skin. This article presents data on pathogenetic applicability and clinical efficacy of emollients with anti-inflammatory compounds in patients with AD.https://vsp.spr-journal.ru/jour/article/view/3033childrenatopic dermatitisatopic marchepidermal barrierstaphylococcus aureuscorneal layertranscutaneous sensibilization |
| spellingShingle | Nikolay N. Murashkin Roza Y. Nezhvedilova Dmitri V. Fedorov Roman V. Epishev Roman A. Ivanov Alexander I. Materikin Leonid A. Opryatin Alena A. Savelova Lyudmila L. Rusakova Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis Вопросы современной педиатрии children atopic dermatitis atopic march epidermal barrier staphylococcus aureus corneal layer transcutaneous sensibilization |
| title | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_full | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_fullStr | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_full_unstemmed | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_short | Scientific and Practical Innovations in Restoring Skin Barrier Properties in Children with Atopic Dermatitis |
| title_sort | scientific and practical innovations in restoring skin barrier properties in children with atopic dermatitis |
| topic | children atopic dermatitis atopic march epidermal barrier staphylococcus aureus corneal layer transcutaneous sensibilization |
| url | https://vsp.spr-journal.ru/jour/article/view/3033 |
| work_keys_str_mv | AT nikolaynmurashkin scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis AT rozaynezhvedilova scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis AT dmitrivfedorov scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis AT romanvepishev scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis AT romanaivanov scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis AT alexanderimaterikin scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis AT leonidaopryatin scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis AT alenaasavelova scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis AT lyudmilalrusakova scientificandpracticalinnovationsinrestoringskinbarrierpropertiesinchildrenwithatopicdermatitis |