Cholestasis and Pulmonary Hypertension in Neonatal Thyrotoxicosis: A Case Report
Neonatal thyrotoxicosis is mostly caused by the transplacental passage of maternal thyroid stimulating hormone (TSH) receptor antibodies (TRAb) to the fetus. Although rare and transient, this condition may be associated with significant morbidity and mortality if not diagnosed and treated in an appr...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-10-01
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| Series: | Dr. Sulaiman Al Habib Medical Journal |
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| Online Access: | https://journals.lww.com/10.1007/s44229-022-00019-6 |
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| author | Ehab Mohamed Hantash Manar Hany Anwar Syeda Naqvi Maha Musri Alzubyania Abdulrahman Abdullah Al Zahrani |
| author_facet | Ehab Mohamed Hantash Manar Hany Anwar Syeda Naqvi Maha Musri Alzubyania Abdulrahman Abdullah Al Zahrani |
| author_sort | Ehab Mohamed Hantash |
| collection | DOAJ |
| description | Neonatal thyrotoxicosis is mostly caused by the transplacental passage of maternal thyroid stimulating hormone (TSH) receptor antibodies (TRAb) to the fetus. Although rare and transient, this condition may be associated with significant morbidity and mortality if not diagnosed and treated in an appropriate and timely manner. Anti-thyroid drugs are the main therapy. Here, we report a preterm newborn that presented with two uncommon presentations of neonatal thyrotoxicosis, cholestasis and pulmonary hypertension that significantly improved following the administration of anti-thyroid medications. |
| format | Article |
| id | doaj-art-e922fa24dc5a4038b8c245b139436d42 |
| institution | DOAJ |
| issn | 2666-819X 2590-3349 |
| language | English |
| publishDate | 2022-10-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dr. Sulaiman Al Habib Medical Journal |
| spelling | doaj-art-e922fa24dc5a4038b8c245b139436d422025-08-20T03:03:19ZengWolters Kluwer Medknow PublicationsDr. Sulaiman Al Habib Medical Journal2666-819X2590-33492022-10-014420520810.1007/s44229-022-00019-6Cholestasis and Pulmonary Hypertension in Neonatal Thyrotoxicosis: A Case ReportEhab Mohamed HantashManar Hany AnwarSyeda NaqviMaha Musri AlzubyaniaAbdulrahman Abdullah Al ZahraniNeonatal thyrotoxicosis is mostly caused by the transplacental passage of maternal thyroid stimulating hormone (TSH) receptor antibodies (TRAb) to the fetus. Although rare and transient, this condition may be associated with significant morbidity and mortality if not diagnosed and treated in an appropriate and timely manner. Anti-thyroid drugs are the main therapy. Here, we report a preterm newborn that presented with two uncommon presentations of neonatal thyrotoxicosis, cholestasis and pulmonary hypertension that significantly improved following the administration of anti-thyroid medications.https://journals.lww.com/10.1007/s44229-022-00019-6thyrotoxicosischolestasishypertension |
| spellingShingle | Ehab Mohamed Hantash Manar Hany Anwar Syeda Naqvi Maha Musri Alzubyania Abdulrahman Abdullah Al Zahrani Cholestasis and Pulmonary Hypertension in Neonatal Thyrotoxicosis: A Case Report Dr. Sulaiman Al Habib Medical Journal thyrotoxicosis cholestasis hypertension |
| title | Cholestasis and Pulmonary Hypertension in Neonatal Thyrotoxicosis: A Case Report |
| title_full | Cholestasis and Pulmonary Hypertension in Neonatal Thyrotoxicosis: A Case Report |
| title_fullStr | Cholestasis and Pulmonary Hypertension in Neonatal Thyrotoxicosis: A Case Report |
| title_full_unstemmed | Cholestasis and Pulmonary Hypertension in Neonatal Thyrotoxicosis: A Case Report |
| title_short | Cholestasis and Pulmonary Hypertension in Neonatal Thyrotoxicosis: A Case Report |
| title_sort | cholestasis and pulmonary hypertension in neonatal thyrotoxicosis a case report |
| topic | thyrotoxicosis cholestasis hypertension |
| url | https://journals.lww.com/10.1007/s44229-022-00019-6 |
| work_keys_str_mv | AT ehabmohamedhantash cholestasisandpulmonaryhypertensioninneonatalthyrotoxicosisacasereport AT manarhanyanwar cholestasisandpulmonaryhypertensioninneonatalthyrotoxicosisacasereport AT syedanaqvi cholestasisandpulmonaryhypertensioninneonatalthyrotoxicosisacasereport AT mahamusrialzubyania cholestasisandpulmonaryhypertensioninneonatalthyrotoxicosisacasereport AT abdulrahmanabdullahalzahrani cholestasisandpulmonaryhypertensioninneonatalthyrotoxicosisacasereport |