The Efficiency, Predictability and Safety Between Custom-Q Femotsecond Laser In Situ Keratomileusis and Second (Visumax 800) Generation Keratorefractive Lenticule Extraction Surgery
<b>Background/Objectives</b>: To evaluate the postoperative outcomes between the second-generation keratorefractive lenticule extraction (KLEx) surgery and femtosecond laser in situ keratomileusis (FS-LASIK). <b>Methods</b>: A retrospective cohort study was conducted and subj...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-03-01
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| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/15/5/634 |
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| Summary: | <b>Background/Objectives</b>: To evaluate the postoperative outcomes between the second-generation keratorefractive lenticule extraction (KLEx) surgery and femtosecond laser in situ keratomileusis (FS-LASIK). <b>Methods</b>: A retrospective cohort study was conducted and subjects received second-generation KLEx and FS-LASIK surgeries were enrolled. A total of 124 and 102 eyes were selected into the second-generation KLEx and FS-LASIK groups after exclusion. The primary outcomes were the postoperative uncorrected distance visual acuity (UDVA), spherical equivalent (SE), amount of astigmatism, and best-correct visual acuity (BCVA). The independent <i>t</i>-test was applied to compare the primary outcomes between groups. <b>Results</b>: The mean UDVA three months postoperatively showed insignificant differences between the two groups (<i>p</i> = 0.999). At the final visit, there were 113 (91.12%) and 96 (94.12%) subjects who reached UDVA 20/20 in the FS-LASIK and second-generation KLEx groups and the difference was statistically insignificant (<i>p</i> = 0.455), and the second-generation KLEx group illustrated a higher UDVA improvement (<i>p</i> = 0.046). The SE three months postoperatively showed insignificant difference between groups, whether the absolute value or the ratio of SE within ±0.50 D or ±1.00 D (all <i>p</i> > 0.05). The vector analysis indicated that the difference vector (DV) was significantly lower in the second-generation KLEx group (<i>p</i> = 0.033). The ratio of loss of more than 1 line BCVA showed insignificant differences between the two groups (all <i>p</i> > 0.05). In addition, the risk of postoperative dry eye disease (DED) was significantly higher in the FS-LASIK group (<i>p</i> = 0.031). <b>Conclusions</b>: The efficiency and predictability between second-generation KLEx and FS-LASIK surgeries are similar, while more DED occurred after FS-LASIK surgery. |
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| ISSN: | 2075-4418 |