Using Protein Homology Models for Structure-Based Studies: Approaches to Model Refinement
Homology modeling is a computational methodology to assign a 3-D structure to a target protein when experimental data are not available. The methodology uses another protein with a known structure that shares some sequence identity with the target as a template. The crudest approach is to thread the...
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| Main Authors: | V. Kairys, M.K. Gilson, Miguel Xavier Fernandes |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2006-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2006.250 |
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