Neutralizing antibody response to different COVID-19 vaccines in Brazil: the impact of previous infection and booster doses

Neutralizing antibody response to different COVID-19 vaccines in Brazil: the impact of previous infection and booster doses

IntroductionIn Brazil, three COVID-19 vaccines were among the first widely used (CoronaVac, ChAdOx1, and BNT162b2), which aimed to induce neutralizing antibodies (NAbs) against the original SARS-CoV-2 strain. Although effective against severe disease, they showed waning NAb levels and reduced effica...

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Main Authors: Beatriz L. L. Caetano, Paolla B. A. Pinto, Agatha R. Pacheco, Agnes R. Lage, Aline S. G. Pereira, Amanda V. P. Nascimento, Thiago R. Machado, Anderson Paulino, Thiago L. Medeiros, Lorena O. Fernandes-Siqueira, Andrea T. Da Poian, Ingrid S. Horbach, Adriana S. Azevedo, Simone M. Costa, Ada M. B. Alves
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
COVID-19
vaccine
neutralizing antibodies
booster dose
SARS-CoV-2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1603612/full
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