Hypoxia-mediated HES4 promotes the proliferation and motility of hepatocellular carcinoma cell by enhancing COL4A2 transcription
Abstract Hypoxia is a key feature of hepatocellular carcinoma (HCC) tissues. On one hand, it can drive HCC cell to alter their energy metabolism; on the other hand, it promotes the activation of multiple signaling pathways, thereby facilitating the progression of HCC. This study aims to explore the...
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| Main Authors: | Pingping Zhao, Hong Xu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-07-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-03152-4 |
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