Idiopathic AA amyloidosis presenting with initial abdominal pain: a case report and literature review

Amyloidosis is a rare disease, often secondary to chronic inflammation or autoimmune disorders, with an unclear etiology in some cases. Herein, we report a 67-year-old male patient presenting with recurrent abdominal pain and multi-system involvement. The diagnosis of AA amyloidosis was confirmed by...

Full description

Saved in:
Bibliographic Details
Main Authors: Pianpian Xia, Deliang Liu, Feihong Deng, Dalian Ou, Mingyang Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1640436/full
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Amyloidosis is a rare disease, often secondary to chronic inflammation or autoimmune disorders, with an unclear etiology in some cases. Herein, we report a 67-year-old male patient presenting with recurrent abdominal pain and multi-system involvement. The diagnosis of AA amyloidosis was confirmed by Congo red staining of small intestinal mucosal and bone marrow biopsies. Despite comprehensive screening, no definite etiology was identified. This case highlights that amyloidosis should be considered in patients with unexplained abdominal pain and multisystem abnormalities, and early tissue biopsy is crucial for diagnosis.
ISSN:2296-858X