Simple and Cost-Effective Generation of 3D Cell Sheets and Spheroids Using Curvature-Controlled Paraffin Wax Substrates

Simple and Cost-Effective Generation of 3D Cell Sheets and Spheroids Using Curvature-Controlled Paraffin Wax Substrates

Abstract The challenges associated with animal testing in pharmaceutical development have driven the search for alternative in vitro models that mimic human tissues more accurately. In this study, we present a simple and cost-effective method for generating 3D cell sheets and spheroids using curvatu...

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Bibliographic Details
Main Authors: Huijung Kim, Kyeong-Mo Koo, Chang-Dae Kim, Min Ji Byun, Chun Gwon Park, Hyungbin Son, Hyung-Ryong Kim, Tae-Hyung Kim
Format: Article
Language:English
Published: SpringerOpen 2024-10-01
Series:Nano Convergence
Subjects:
Paraffin wax
Cell sheet
Spheroids
Periodontal ligament cell
Mesenchymal stem cell
Quantum dots
Online Access:https://doi.org/10.1186/s40580-024-00451-4
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