The safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) surgery for the treatment of lumbar disc herniation
BackgroundThe purpose of this study is to discuss the safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar disc herniation.MethodsFrom August 2018 to December 2021, patients with lumbar disc herniation who received TLIF treatment were included in this...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1598531/full |
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| author | Wei Wang Zhao Guo Lixin Yang Jianning Liu Zhiyong Li Jiaqi Li Hong Zhao Tao Sun |
| author_facet | Wei Wang Zhao Guo Lixin Yang Jianning Liu Zhiyong Li Jiaqi Li Hong Zhao Tao Sun |
| author_sort | Wei Wang |
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| description | BackgroundThe purpose of this study is to discuss the safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar disc herniation.MethodsFrom August 2018 to December 2021, patients with lumbar disc herniation who received TLIF treatment were included in this study. Clinical data collected during both the preoperative period and the 2-year postoperative follow-up were analyzed. The correlations between preoperative clinical indicators and postoperative functional outcomes were modeled using both univariate regression and multivariable-adjusted analyses.ResultThe study population comprised 547 consecutive cases (male: 261, 47.7%; female: 286, 52.3%). Stratified outcome analysis showed 458 patients (83.7%) attained optimal surgical recovery without detectable morbidity, contrasted with 89 cases (16.3%) manifesting postoperative complications. The univariate analysis of postoperative complications found that the recurrence of symptoms was related to body mass index (BMI), preoperative pain time, High-level segment, intraoperative bleeding volume and postoperative visual analog scale (VAS)-back. Postoperative hematoma was related to hypertension and wound drainage. Poor wound healing was related to BMI and Wound drainage volume. However, this study failed to find the related factors of wound infection. After binary logistic analysis of the above single factors, we found that BMI and preoperative pain time were independent risk factors for symptom recurrence, and BMI were independent risk factors for Poor wound healing.ConclusionTransforaminal lumbar interbody fusion surgery can safely and effectively treat lumbar disc herniation. |
| format | Article |
| id | doaj-art-e913d024af76493db55604e62df23a72 |
| institution | OA Journals |
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| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Surgery |
| spelling | doaj-art-e913d024af76493db55604e62df23a722025-08-20T02:15:20ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2025-05-011210.3389/fsurg.2025.15985311598531The safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) surgery for the treatment of lumbar disc herniationWei Wang0Zhao Guo1Lixin Yang2Jianning Liu3Zhiyong Li4Jiaqi Li5Hong Zhao6Tao Sun7Department of Orthopedics, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, ChinaDepartment of Orthopedics, Affiliated Hospital of Hebei University, Baoding, Hebei, ChinaDepartment of Orthopedics, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, ChinaDepartment of Orthopedics, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, ChinaDepartment of Orthopedics, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, ChinaDepartment of Orthopedics, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, ChinaDepartment of Eye Trauma, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, ChinaDepartment of Orthopedics, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, ChinaBackgroundThe purpose of this study is to discuss the safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar disc herniation.MethodsFrom August 2018 to December 2021, patients with lumbar disc herniation who received TLIF treatment were included in this study. Clinical data collected during both the preoperative period and the 2-year postoperative follow-up were analyzed. The correlations between preoperative clinical indicators and postoperative functional outcomes were modeled using both univariate regression and multivariable-adjusted analyses.ResultThe study population comprised 547 consecutive cases (male: 261, 47.7%; female: 286, 52.3%). Stratified outcome analysis showed 458 patients (83.7%) attained optimal surgical recovery without detectable morbidity, contrasted with 89 cases (16.3%) manifesting postoperative complications. The univariate analysis of postoperative complications found that the recurrence of symptoms was related to body mass index (BMI), preoperative pain time, High-level segment, intraoperative bleeding volume and postoperative visual analog scale (VAS)-back. Postoperative hematoma was related to hypertension and wound drainage. Poor wound healing was related to BMI and Wound drainage volume. However, this study failed to find the related factors of wound infection. After binary logistic analysis of the above single factors, we found that BMI and preoperative pain time were independent risk factors for symptom recurrence, and BMI were independent risk factors for Poor wound healing.ConclusionTransforaminal lumbar interbody fusion surgery can safely and effectively treat lumbar disc herniation.https://www.frontiersin.org/articles/10.3389/fsurg.2025.1598531/fulltransforaminal lumbar interbody fusionlumbar disc herniationpostoperative complicationssymptoms recurrencerisk factors |
| spellingShingle | Wei Wang Zhao Guo Lixin Yang Jianning Liu Zhiyong Li Jiaqi Li Hong Zhao Tao Sun The safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) surgery for the treatment of lumbar disc herniation Frontiers in Surgery transforaminal lumbar interbody fusion lumbar disc herniation postoperative complications symptoms recurrence risk factors |
| title | The safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) surgery for the treatment of lumbar disc herniation |
| title_full | The safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) surgery for the treatment of lumbar disc herniation |
| title_fullStr | The safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) surgery for the treatment of lumbar disc herniation |
| title_full_unstemmed | The safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) surgery for the treatment of lumbar disc herniation |
| title_short | The safety and effectiveness of transforaminal lumbar interbody fusion (TLIF) surgery for the treatment of lumbar disc herniation |
| title_sort | safety and effectiveness of transforaminal lumbar interbody fusion tlif surgery for the treatment of lumbar disc herniation |
| topic | transforaminal lumbar interbody fusion lumbar disc herniation postoperative complications symptoms recurrence risk factors |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1598531/full |
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