Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular Carcinoma

Superior sulcus tumors, also known as Pancoast tumors, present in a distinctive way with Horner's syndrome (ptosis, miosis, and anhidrosis), hand weakness brought on by the atrophy of the intrinsic hand muscles, and excruciating pain along the medial aspect of the arm. (1) Primary lung cancers...

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Main Authors: Lakshmi Sandhya Singuluri, Prasanth Ganesan, Bheemanathi Hanuman Srinivas, Biswajit Dubashi, Yadav Nisha
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd.
Series:Indian Journal of Medical and Paediatric Oncology
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1769492
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author Lakshmi Sandhya Singuluri
Prasanth Ganesan
Bheemanathi Hanuman Srinivas
Biswajit Dubashi
Yadav Nisha
author_facet Lakshmi Sandhya Singuluri
Prasanth Ganesan
Bheemanathi Hanuman Srinivas
Biswajit Dubashi
Yadav Nisha
author_sort Lakshmi Sandhya Singuluri
collection DOAJ
description Superior sulcus tumors, also known as Pancoast tumors, present in a distinctive way with Horner's syndrome (ptosis, miosis, and anhidrosis), hand weakness brought on by the atrophy of the intrinsic hand muscles, and excruciating pain along the medial aspect of the arm. (1) Primary lung cancers constitute a majority of Pancoast tumors, but Pancoast syndrome can be multifactorial. (2) Here, we present a case of 62-year-old male who presented with right shoulder pain and weakness for 2 months. Clinically, he had a supraclavicular mass with atrophy of the intrinsic muscles of the hand and sensory-motor weakness. Computed tomography showed a mass lesion in the supraclavicular fossa with the erosion of the T1 vertebra and first rib, mimicking carcinoma right upper lobe. However, the biopsy from the mass was suggestive of metastasis from hepatocellular carcinoma (HCC). Our case report identifies HCC as a rare differential for Pancoast syndrome and highlights the unique metastatic presentation.
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publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-e913841e4b8a4be492fb7928cec3b04d2025-08-20T02:32:44ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-212910.1055/s-0043-1769492Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular CarcinomaLakshmi Sandhya Singuluri0https://orcid.org/0009-0006-9774-8008Prasanth Ganesan1https://orcid.org/0000-0003-2762-6591Bheemanathi Hanuman Srinivas2Biswajit Dubashi3https://orcid.org/0000-0001-9852-2525Yadav Nisha4Department of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, IndiaDepartment of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, IndiaDepartment of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, IndiaDepartment of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, IndiaDepartment of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, IndiaSuperior sulcus tumors, also known as Pancoast tumors, present in a distinctive way with Horner's syndrome (ptosis, miosis, and anhidrosis), hand weakness brought on by the atrophy of the intrinsic hand muscles, and excruciating pain along the medial aspect of the arm. (1) Primary lung cancers constitute a majority of Pancoast tumors, but Pancoast syndrome can be multifactorial. (2) Here, we present a case of 62-year-old male who presented with right shoulder pain and weakness for 2 months. Clinically, he had a supraclavicular mass with atrophy of the intrinsic muscles of the hand and sensory-motor weakness. Computed tomography showed a mass lesion in the supraclavicular fossa with the erosion of the T1 vertebra and first rib, mimicking carcinoma right upper lobe. However, the biopsy from the mass was suggestive of metastasis from hepatocellular carcinoma (HCC). Our case report identifies HCC as a rare differential for Pancoast syndrome and highlights the unique metastatic presentation.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1769492hepatocellular carcinomaPancoast tumorPancoast syndromemetastasishepatoid adenocarcinoma
spellingShingle Lakshmi Sandhya Singuluri
Prasanth Ganesan
Bheemanathi Hanuman Srinivas
Biswajit Dubashi
Yadav Nisha
Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular Carcinoma
Indian Journal of Medical and Paediatric Oncology
hepatocellular carcinoma
Pancoast tumor
Pancoast syndrome
metastasis
hepatoid adenocarcinoma
title Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular Carcinoma
title_full Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular Carcinoma
title_fullStr Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular Carcinoma
title_full_unstemmed Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular Carcinoma
title_short Case Report with a Review of Literature: Pancoast Syndrome—A Rare Presentation of Metastatic Hepatocellular Carcinoma
title_sort case report with a review of literature pancoast syndrome a rare presentation of metastatic hepatocellular carcinoma
topic hepatocellular carcinoma
Pancoast tumor
Pancoast syndrome
metastasis
hepatoid adenocarcinoma
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1769492
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