Atypical Focal Choroidal Excavation with Macular Hole in a Patient with Alagille Syndrome
This study is aimed at reporting a rare and unusual focal choroidal excavation with a macular hole in a patient with Alagille syndrome (AGS). A 21-year-old woman with an established early-life AGS diagnosis was referred to our hospital prior to liver transplantation. Examination revealed best-correc...
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| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2022/8136115 |
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| author | Manami Misawa Hironobu Tampo Shinji Makino |
| author_facet | Manami Misawa Hironobu Tampo Shinji Makino |
| author_sort | Manami Misawa |
| collection | DOAJ |
| description | This study is aimed at reporting a rare and unusual focal choroidal excavation with a macular hole in a patient with Alagille syndrome (AGS). A 21-year-old woman with an established early-life AGS diagnosis was referred to our hospital prior to liver transplantation. Examination revealed best-corrected visual acuity of 16/20 and 20/20 in the right and left eye, respectively. Slit-lamp examination was positive for posterior embryotoxon in both eyes. Fundoscopy revealed diffuse choroidal hypopigmentation with increased visibility of the choroidal blood vessels and circumferential chorioretinal atrophy in the mid-peripheral and peripheral retina in both eyes. A full-thickness macular hole with underlying focal choroidal excavation was observed in the right eye. Optical coherence tomography through the macula confirmed choroidal excavation with a full-thickness macular hole in the right eye. To our knowledge, this is the first report describing focal choroidal excavation with a macular hole in an AGS patient. |
| format | Article |
| id | doaj-art-e90ea4089c594adb9c5135f07a3d5f1e |
| institution | OA Journals |
| issn | 2090-6730 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-e90ea4089c594adb9c5135f07a3d5f1e2025-08-20T02:21:53ZengWileyCase Reports in Ophthalmological Medicine2090-67302022-01-01202210.1155/2022/8136115Atypical Focal Choroidal Excavation with Macular Hole in a Patient with Alagille SyndromeManami Misawa0Hironobu Tampo1Shinji Makino2Department of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyThis study is aimed at reporting a rare and unusual focal choroidal excavation with a macular hole in a patient with Alagille syndrome (AGS). A 21-year-old woman with an established early-life AGS diagnosis was referred to our hospital prior to liver transplantation. Examination revealed best-corrected visual acuity of 16/20 and 20/20 in the right and left eye, respectively. Slit-lamp examination was positive for posterior embryotoxon in both eyes. Fundoscopy revealed diffuse choroidal hypopigmentation with increased visibility of the choroidal blood vessels and circumferential chorioretinal atrophy in the mid-peripheral and peripheral retina in both eyes. A full-thickness macular hole with underlying focal choroidal excavation was observed in the right eye. Optical coherence tomography through the macula confirmed choroidal excavation with a full-thickness macular hole in the right eye. To our knowledge, this is the first report describing focal choroidal excavation with a macular hole in an AGS patient.http://dx.doi.org/10.1155/2022/8136115 |
| spellingShingle | Manami Misawa Hironobu Tampo Shinji Makino Atypical Focal Choroidal Excavation with Macular Hole in a Patient with Alagille Syndrome Case Reports in Ophthalmological Medicine |
| title | Atypical Focal Choroidal Excavation with Macular Hole in a Patient with Alagille Syndrome |
| title_full | Atypical Focal Choroidal Excavation with Macular Hole in a Patient with Alagille Syndrome |
| title_fullStr | Atypical Focal Choroidal Excavation with Macular Hole in a Patient with Alagille Syndrome |
| title_full_unstemmed | Atypical Focal Choroidal Excavation with Macular Hole in a Patient with Alagille Syndrome |
| title_short | Atypical Focal Choroidal Excavation with Macular Hole in a Patient with Alagille Syndrome |
| title_sort | atypical focal choroidal excavation with macular hole in a patient with alagille syndrome |
| url | http://dx.doi.org/10.1155/2022/8136115 |
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