Advances in the development of nanomedicines for treating chronic kidney disease

Chronic kidney disease(CKD) is a group of chronic diseases with high morbidity and mortality. There is no effective curative therapeutic for CKD. Traditional therapeutics of CKD have major disadvantages, such as poor renal-targeting property and serious side effects. The latest evidence shows that n...

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Main Authors: He Yu-han, Li Yu-pei, Su Bai-hai
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2025-06-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2025.06.010
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author He Yu-han
Li Yu-pei
Su Bai-hai
author_facet He Yu-han
Li Yu-pei
Su Bai-hai
author_sort He Yu-han
collection DOAJ
description Chronic kidney disease(CKD) is a group of chronic diseases with high morbidity and mortality. There is no effective curative therapeutic for CKD. Traditional therapeutics of CKD have major disadvantages, such as poor renal-targeting property and serious side effects. The latest evidence shows that nanomedicines have great potential in the treatment of CKD. Nanomedicines provide good physicochemical properties and biological characteristics, and can precisely deliver the loaded drug to the kidneys to improve the therapeutic effect of CKD. In this review, we first reviewed the pathological mechanisms of CKD progression, and then discussed recent advances in the use of nanomedicines for CKD treatment.
format Article
id doaj-art-e90de38f7dae475cb67ddc73d2f898b1
institution Kabale University
issn 1671-2390
language zho
publishDate 2025-06-01
publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-e90de38f7dae475cb67ddc73d2f898b12025-08-20T03:31:27ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902025-06-0125516520112447772Advances in the development of nanomedicines for treating chronic kidney diseaseHe Yu-hanLi Yu-peiSu Bai-haiChronic kidney disease(CKD) is a group of chronic diseases with high morbidity and mortality. There is no effective curative therapeutic for CKD. Traditional therapeutics of CKD have major disadvantages, such as poor renal-targeting property and serious side effects. The latest evidence shows that nanomedicines have great potential in the treatment of CKD. Nanomedicines provide good physicochemical properties and biological characteristics, and can precisely deliver the loaded drug to the kidneys to improve the therapeutic effect of CKD. In this review, we first reviewed the pathological mechanisms of CKD progression, and then discussed recent advances in the use of nanomedicines for CKD treatment.http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2025.06.010Chronic kidney diseaseNanomedicinesRenal deliveryTreatment
spellingShingle He Yu-han
Li Yu-pei
Su Bai-hai
Advances in the development of nanomedicines for treating chronic kidney disease
Linchuang shenzangbing zazhi
Chronic kidney disease
Nanomedicines
Renal delivery
Treatment
title Advances in the development of nanomedicines for treating chronic kidney disease
title_full Advances in the development of nanomedicines for treating chronic kidney disease
title_fullStr Advances in the development of nanomedicines for treating chronic kidney disease
title_full_unstemmed Advances in the development of nanomedicines for treating chronic kidney disease
title_short Advances in the development of nanomedicines for treating chronic kidney disease
title_sort advances in the development of nanomedicines for treating chronic kidney disease
topic Chronic kidney disease
Nanomedicines
Renal delivery
Treatment
url http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2025.06.010
work_keys_str_mv AT heyuhan advancesinthedevelopmentofnanomedicinesfortreatingchronickidneydisease
AT liyupei advancesinthedevelopmentofnanomedicinesfortreatingchronickidneydisease
AT subaihai advancesinthedevelopmentofnanomedicinesfortreatingchronickidneydisease